Species: Hu
Applications: WB, Flow
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
BRCA1-associated protein 1 (BAP1) is a ubiquitin hydrolase that acts as a BRCA1 growth control pathway tumor suppressor. Specifically, BAP-1 localizes to the nucleus where it interferes with the BRCA1/BARD1 heterodimer activity and mediates deubiquitination of histone H2A and HCFC1. BAP 1 is highly expressed in testis, placenta, breast and ovary.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
8314 |
Alternate Names |
- BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
- BRCA1-associated protein 1
- Cerebral protein 6
- cerebral protein-13
- cerebral protein-6
- DKFZp686N04275
- EC 3.4.19.12
- FLJ35406
- FLJ37180
- hucep-6
- KIAA0272HUCEP-13
- ubiquitin carboxyl-terminal hydrolase BAP1
- ubiquitin carboxy-terminal hydrolase
- UCHL2
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