ATG4D Antibody (222CT15.4.1)

Product Discontinued

ATG4D Antibody (222CT15.4.1) Summary

• Immunogen: This ATG4D monoclonal antibody is generated from mouse immunized with ATG4D recombinant protein.
• Localization: Cellular Location Cysteine protease ATG4D: Cytoplasm. Tissue Location Mainly expressed in skeletal muscle and, to a lower extent, in testis
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ATG4D
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:50
  • Western Blot 1:100 - 1:1000
• Theoretical MW: 52.922 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 0.6 mg/ml
• Purity: Protein G purified

Alternate Names for ATG4D Antibody (222CT15.4.1)

• APG4 autophagy 4 homolog D (S. cerevisiae)
• APG4 autophagy 4 homolog D
• APG4D
• APG4-D
• ATG4 autophagy related 4 homolog D (S. cerevisiae)
• AUTL4
• AUT-like 4 cysteine endopeptidase
• AUT-like 4, cysteine endopeptidase (S. cerevisiae)
• AUT-like 4, cysteine endopeptidase
• autophagin-4
• Autophagy-related cysteine endopeptidase 4
• Autophagy-related protein 4 homolog D
• cysteine protease ATG4D
• cysteine protease involved in autophagy
• EC 3.4.22
• EC 3.4.22.-

Background

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ATG4D
• Uniprot:
  • Q86TL0(Human)