Human Asialoglycoprotein Receptor 2 ELISA Kit (Colorimetric)

ELISA: Human Asialoglycoprotein Receptor 2 ELISA Kit (Colorimetric) [NBP2-69872] - Samples were spiked with high concentrations of Human Asialoglycoprotein Receptor 2 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

ELISA: Human Asialoglycoprotein Receptor 2 ELISA Kit (Colorimetric) [NBP2-69872] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma and other biological fluids
• Standard Curve Range: 0.16 - 10 ng/mL
• Sensitivity: 0.10 ng/mL

Human Asialoglycoprotein Receptor 2 ELISA Kit (Colorimetric) Summary

• Specificity: This kit recognizes Human ASGR2 in samples. No significant cross-reactivity or interference between Human ASGR2 and analogues was observed.
• Standard Curve Range: 0.16 - 10 ng/mL
• Sensitivity: 0.10 ng/mL
• Assay Type: Sandwich-ELISA
• Inter-Assay: CV% < 5.07%
• Intra-Assay: CV% < 5.05%
• Spike Recovery: 90-107%
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: ASGR2

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human Asialoglycoprotein Receptor 2 ELISA Kit (Colorimetric)

• ASGPR 2
• ASGP-R 2
• ASGPR2
• ASGP-R2
• ASGR2
• asialoglycoprotein receptor 2
• CLEC4H2
• CLEC4H2FLJ60040
• C-type lectin domain family 4 member H2
• HBxAg-binding protein
• HBXBP
• Hepatic lectin H2
• HL-2

Background

Asialoglycoprotein Receptor 2 is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of plasma glycoproteins in which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. It is expressed exclusively in hepatic parenchymal cells and calcium is required for ligand binding. Asialoglycoprotein Receptor 2 may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. Asialoglycoprotein Receptor 2 is involved in hepatitis B, hepatitis C, liver cirrhosis, hepatocellular carcinoma, nephropathy, leukemia, urethritis, autoimmune hepatitis, alcoholic liver cirrhosis, and jaundice.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: ASGR2