ARHGEF11 Antibody (2F4)

Images

 
Western Blot: ARHGEF11 Antibody (2F4) [H00009826-M02] - ARHGEF11 monoclonal antibody (M02), clone 2F4. Analysis of ARHGEF11 expression in human colon.
Sandwich ELISA: ARHGEF11 Antibody (2F4) [H00009826-M02] - Detection limit for recombinant GST tagged ARHGEF11 is approximately 0.3ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
2F4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

ARHGEF11 Antibody (2F4) Summary

Immunogen
ARHGEF11 (AAH57394, 651 a.a. ~ 750 a.a) partial recombinant protein with GST tag.RSESLKGREEMKRSRKAENVPRSRSDVDMDAAAEATRLHQSASSSTSSLSTRSLENPTPPFTPKMGRRSIESPSLGFCTDTLLPHLLEDDLGQLSDLEPE
Specificity
ARHGEF11 - Rho guanine nucleotide exchange factor (GEF) 11
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
ARHGEF11
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ARHGEF11 Antibody (2F4)

  • DKFZp667F1223
  • glutamate transporter EAAT4-associated protein 48
  • GTRAP48
  • KIAA0380rho guanine nucleotide exchange factor 11
  • PDZ-RHOGEF
  • Rho guanine exchange factor (GEF) 11
  • Rho guanine nucleotide exchange factor (GEF) 11
  • RhoA-specific guanine nucleotide exchange factor
  • RhoGEF glutamate transport modulator

Background

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ARHGEF11
Entrez
OMIM
Uniprot