Aquaporin-5 Antibody

Images

 
Western Blot: Aquaporin-5 Antibody [NBP1-19755] - Analysis of AQP5 (Y243) pAb at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:Jurkat cell lysate Lane3:PC12 cell lysate Lane4:sp2/0 cell lysate
Immunohistochemistry-Paraffin: Aquaporin-5 Antibody [NBP1-19755] - Analyzes of AQP5 (Y243) pAb in paraffin-embedded human lung carcinoma tissue at 1:100
Western Blot: Aquaporin-5 Antibody [NBP1-19755] - Aquaporin-5 Antibody extracts from HUVECcells.
Immunohistochemistry-Paraffin: Aquaporin-5 Antibody [NBP1-19755] - Immunohistochemistry (IHC) analyzes of AQP5 (Y243) pAb in paraffin-embedded human lung carcinoma tissue.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-19755
    • Availability
      Product Discontinued

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Aquaporin-5 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 220-270 of Human AQP5.
Clonality
Polyclonal
Host
Rabbit
Gene
AQP5
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
Theoretical MW
36 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Aquaporin-5 Antibody

  • AQP-5
  • aquaporin 5
  • aquaporin-5

Background

Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. At least ten isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP9. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7 and AQP9 are permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. In the lung, the 27-kDa AQP5 is responsible for the majority of water transport across the apical membrane of type I alveolar epithelial cells. The gene encoding human AQP5 maps to chromosome 12q13.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol AQP5
Entrez
Uniprot