APJ/Apelin receptor Antibody (MM0095-7D42)

Product Discontinued

APJ/Apelin receptor Antibody (MM0095-7D42) Summary

• Immunogen: Human Apelin receptor
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: APLNR
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: A 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with 0.2 ml sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for APJ/Apelin receptor Antibody (MM0095-7D42)

• AGTRL1
• AGTRL1HG11
• angiotensin II receptor-like 1
• Angiotensin receptor-like 1
• apelin receptor
• APJ (apelin) receptor
• APJ receptor
• APJ
• APJFLJ96609
• APJR
• APLNR
• FLJ90771
• G protein-coupled receptor APJ
• G-protein coupled receptor APJ
• G-protein coupled receptor HG11
• HG11 orphan receptor
• HG11
• MGC45246

Background

APJ or Apelin Receptor, is an angiotensin-1-like receptor that is expressed abundantly in the corpus callosum and spinal cord. The human apelin receptor has been localized to chromosome 11. In porcine spinal cord, APJ mRNA was detected at a higher level in white matter than in gray matter (Matsumoto et al., 1996). APJ binds apelin, which induces cell acidification (Tatemoto et al., 1998). APJ expression has been reported in blood, brain, spinal cord, and vessel. ESTs have been isolated from brain, head/neck, lung, and placenta libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for APJ/Apelin receptor Antibody (NBP2-12043)(1)

Publication using NBP2-12043

• Cui RR, Mao DA, Yi L et al. Apelin suppresses apoptosis of human vascular smooth muscle cells via APJ/PI3-K/Akt signaling pathways. Amino Acids 2010-11-01 [PMID: 20495838] (WB, Human, Hamster)

Bioinformatics

• Gene Symbol: APLNR
• Uniprot:
  • P35414()