AP-2 gamma Antibody (AP2g 6E4/4)

Product Discontinued

AP-2 gamma Antibody (AP2g 6E4/4) Summary

• Immunogen: Bacterially produced AP-2a/AP-2g fusion protein (c-terminal half of AP-2 gamma)
• Epitope: C terminus.
• Localization: Nuclear
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: TFAP2C
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10 - 1:500
  • Immunoprecipitation 1:10 - 1:500
  • Western Blot 1:100 - 1:2000
• Application Notes: Positive control(s): MCF7 cells. Antigen recovery will improve staining on paraffin sections.
• Theoretical MW: 50 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for AP-2 gamma Antibody (AP2g 6E4/4)

• Activating enhancer-binding protein 2 gamma
• AP2 gamma
• AP-2 gamma
• AP2-GAMMA
• ERF1
• estrogen receptor factor 1
• hAP-2g
• TFAP2C
• TFAP2G
• transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
• transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma)
• transcription factor AP-2 gamma
• Transcription factor ERF-1

Background

AP2 gamma is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TFAP2C
• Entrez:
  • 7022(Human)
  • 21420(Mouse)