AP-2 epsilon/TFAP2E Antibody [Alexa Fluor® 405]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 405

AP-2 epsilon/TFAP2E Antibody [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived recombinant human AP-2ε
  Ala123-Val217
  Accession # Q6VUC0
• Specificity: Detects human AP-2 epsilon in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross‑reactivity with recombinant human (rh) AP‑2 alpha , rhAP‑2 beta , rhAP‑2δ, and rhAP‑2 gamma is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for AP-2 epsilon/TFAP2E Antibody [Alexa Fluor® 405]

• Activating enhancer-binding protein 2-epsilon
• adaptor-related protein complex 2, epsilon subunit
• AP2 epsilon
• AP-2 epsilon
• AP2E
• AP2-epsilon
• MGC49007
• TFAP2E
• transcription factor AP-2 epsilon (activating enhancer binding protein 2epsilon)
• transcription factor AP-2-epsilon

Background

AP-2 epsilon (Activating protein 2 epsilon) is a 48 kDa member of the AP-2 transcription factor family. It is found in embryonic olfactory bulb mitral cells and adult keratinocytes and chondrocytes. In the nucleus, it presumably forms homodimers and heterodimers with other AP‑2 family members. Human AP‑2 epsilon is 442 amino acids in length. It contains a Gln/Pro-rich transactivation domain (aa 22‑122), a DNA binding domain (aa 216‑286) and an AP‑2, helix‑span‑helix dimerization region (aa 287‑417). There is one potential alternate start site at Met09. Over aa 123‑217, human AP‑2 epsilon shares 86% aa identity with mouse AP‑2 epsilon .

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.