Angiostatin Native Protein

Product Discontinued

Angiostatin Native Protein Summary

• Description: Native Angiostatin
  
  

  Source:Human Plasma

• Source: Human Plasma
• Protein/Peptide Type: Native Protein
• Gene: PLG
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 50 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 20 mM HEPES, 150 mM NaCl, pH 7.4
• Concentration: 7.5 mg/ml
• Purity: >95%, by SDS-PAGE

Alternate Names for Angiostatin Native Protein

• Angiostatin
• HAE4

Background

Angiostatin is a proteolytic fragment of plasminogen constituting kringles 1 - 4. It is a potent angiogenesis inhibitor and the inhibition of angiogenesis by angiostatin is directly related to inhibiting the proliferation of endothelial cells. Human Angiostatin significantly inhibits bFGF-induced endothelial cell proliferation and migration at concentrations ranging from 300 nM 1.0uM.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: PLG