Angiopoietin-like Protein 2/ANGPTL2 Antibody (239829) [Unconjugated]

• Reactivity: Hu
• Applications: WB
• Clone: 239829
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

Angiopoietin-like Protein 2/ANGPTL2 Antibody (239829) [Unconjugated] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Angiopoietin-like 2
  Ile233-Phe492
  Accession # Q9UKU9
• Specificity: Detects human Angiopoietin-like 2 in direct ELISAs and Western blots. Shows 25-100% cross‑reactivity with recombinant mouse
  Angiopoietin-like 2 and no cross-reactivity with recombinant human (rh) Angiopoietin-1 or rhAngiopoietin-2.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: ANGPTL2
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Angiopoietin-like Protein 2/ANGPTL2 Antibody (239829) [Unconjugated]

• angiopoietin-like 2
• Angiopoietin-like Protein 2
• angiopoietin-related protein 2
• ANGPTL2
• ANGRP2
• ARP2HARP
• MGC8889

Background

Angiopoietin-like 2, also known as Ang-related protein 2, is a secreted glycoprotein that is structurally related to angiopoietin. It does not bind the Tie-1 or Tie-2 receptors. Angiopoietin-like 2 induces sprouting but is not mitogenic in endothelial cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Angiopoietin-like Protein 2/ANGPTL2 Antibody (MAB2084)(2)

Publications using MAB2084

• Mohamed Zaki Kenawy, Jehan Hasan Sabry, Essam Mohamed Akl, Noha A.H. Emam Angiopoietin-Like Protein 2 in Psoriasis: a New Linkage with Metabolic Syndrome Advances in Dermatology and Allergology 2020-03-09 [PMID: 32467690]
• Sasaki Y, Ohta M, Desai D, Figueiredo J, Whelan M, Sugano T, Yamabi M, Yano W, Faits T, Yabusaki K, Zhang H, Mlynarchik A, Inoue K, Mizuno K, Aikawa M Angiopoietin Like Protein 2 (ANGPTL2) Promotes Adipose Tissue Macrophage and T lymphocyte Accumulation and Leads to Insulin Resistance. PLoS ONE, 2015-07-01;10(7):e0131176. 2015-07-01 [PMID: 26132105] (Western Blot, Human)

Bioinformatics

• Gene Symbol: ANGPTL2
• Uniprot:
  • Q9UKU9()