alpha-Sarcoglycan Antibody (769109) [DyLight 550]

• Reactivity: Hu
• Applications: WB
• Clone: 769109
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 550

alpha-Sarcoglycan Antibody (769109) [DyLight 550] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human alpha -Sarcoglycan
  Gln24-Ala290 (predicted)
  Accession # Q16586
• Specificity: Detects human alpha -Sarcoglycan in direct ELISAs and Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: SGCA
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for alpha-Sarcoglycan Antibody (769109) [DyLight 550]

• 50-DAG
• Adhalin
• ADL
• alphaSarcoglycan
• alpha-Sarcoglycan
• DAG2
• DMDA2
• DMDA250kD DAG
• Dystroglycan-2
• LGMD2D
• LGMD2Dalpha (50kD dystrophin-associated glycoprotein)
• sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
• SCARMD1
• SGCA

Background

The dystrophin-glycoprotein complex (DGC) comprises a group of proteins that are critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Components of the DGC include dystrophin (MIM 300377), which is deficient in Duchenne muscular dystrophy (DMD; MIM 310200); syntrophins (e.g., MIM 600026); dystroglycans (MIM 128239); and sarcoglycans, such as adhalin, a 50-kD transmembrane protein (Roberds et al., 1993 [PubMed 8226900]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SGCA