alpha-Aminoadipate Aminotransferase Antibody [Janelia Fluor® 669]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Janelia Fluor 669

alpha-Aminoadipate Aminotransferase Antibody [Janelia Fluor® 669] Summary

• Immunogen: E. coli-derived recombinant human alpha -Aminoadipate Aminotransferase
  Met1-Leu425
  Accession # Q8N5Z0
• Specificity: Detects human alpha -Aminoadipate Aminotransferase in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: AADAT
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for alpha-Aminoadipate Aminotransferase Antibody [Janelia Fluor® 669]

• AADAT
• alphaAminoadipate Aminotransferase
• alpha-Aminoadipate Aminotransferase
• aminoadipate aminotransferase
• EC 2.6.1.39,2-aminoadipate aminotransferase
• EC 2.6.1.7,2-aminoadipate transaminase
• KAT/AadAT
• KAT2
• KAT2mitochondrial
• Kynurenine aminotransferase II
• Kynurenine--oxoglutarate aminotransferase II
• Kynurenine--oxoglutarate transaminase II
• L kynurenine/alpha aminoadipate aminotransferase

Background

Aminoadipate aminotransferase (AADAT) is a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AADAT