alpha-2A Adrenergic R/ADRA2A Antibody - BSA Free

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Western Blot: alpha-2A Adrenergic R/ADRA2A Antibody [NBP3-10657] - Western blot analysis of alpha-2A Adrenergic R/ADRA2A in Fetal Thymus as a positive control. Antibody dilution at 1.0 ug/ml

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
0.5 mg/ml

Order Details

alpha-2A Adrenergic R/ADRA2A Antibody - BSA Free Summary

Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human alpha-2A Adrenergic R/ADRA2A (NP_000672). Peptide sequence RRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAK
Clonality
Polyclonal
Host
Rabbit
Gene
ADRA2A
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml
Theoretical MW
49 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for alpha-2A Adrenergic R/ADRA2A Antibody - BSA Free

  • a-2A AdrenergicR
  • ADRA2
  • ADRA2A
  • ADRA2Ralpha-2-adrenergic receptor, platelet type
  • ADRARZNF32
  • adrenergic, alpha-2A-, receptor
  • Alpha-2 adrenergic receptor subtype C10
  • alpha-2A Adrenergic R
  • alpha-2A adrenergic receptor
  • alpha2A AdrenergicR
  • Alpha-2A adrenoceptor
  • Alpha-2A adrenoreceptor
  • alpha-2AAR subtype C10
  • ALPHA2AAR
  • Alpha-2AAR
  • ZNF32

Background

This study investigates the involvement of alpha2-adrenergic receptors (AR) in mouse brain induced by a low dose of methamphetamine (METH, 2 mg/kg). Immunohistochemical studies show that alpha2A-AR increased in the dentate gyrus area of the hippocampus 24 h after five repeated administrations of METH. The hippocampal alpha2A-AR proteins rose 3.2-fold when compared to the saline-administered mice. The other adrenergic receptor, alpha1D-AR, were not changed by the treatment. Moreover, alphao-subunits of GTP-binding proteins (Galphao), one of the downstream molecules of alpha2A-AR, was also increased by the treatment. These suggest that the repeated administration of low-doses of METH causes quantitative changes of the signaling of alpha2A-AR in the mouse hippocampus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ADRA2A