alpha-1D Adrenergic R/ADRA1D Antibody

Immunohistochemistry-Paraffin: alpha-1D Adrenergic R/ADRA1D Antibody [NLS12] - Anti-ADRA1D antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: alpha-1D Adrenergic R/ADRA1D Antibody [NLS12] - Analysis of anti-ADRA1D antibody with human prostate.

• Reactivity: Hu, Po, Bt, Bv, Ca, Eq, Mk, Pm, Rb, Mu, Rt, Ha, Sh
• Applications: IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 1.0 mg/ml

alpha-1D Adrenergic R/ADRA1D Antibody Summary

• Immunogen: Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human ADRA1D.
• Specificity: Human ADRA1D. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Mouse (90%), Rat (90%), Hamster (90%), Sheep (90%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ADRA1D
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 5 - 25 ug/ml

Reactivity Notes

Gorilla, Marmoset. Predicted cross-reactivity based on sequence identity: Panda.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for alpha-1D Adrenergic R/ADRA1D Antibody

• a-1D AdrenergicR
• ADRA1
• ADRA1ADAR
• ADRA1D
• ADRA1R
• adrenergic, alpha -1D-, receptor
• adrenergic, alpha-1A-, receptor
• adrenergic, alpha-1D-, receptor
• ALPHA1
• Alpha-1A adrenergic receptor
• alpha-1D Adrenergic R
• alpha-1D adrenergic receptor
• alpha1D AdrenergicR
• Alpha-1D adrenoceptor
• Alpha-1D adrenoreceptor
• alpha-1D-adrenergic receptor
• Alpha-adrenergic receptor 1a
• DAR
• dJ779E11.2

Background

The alpha 1d-adrenoceptor is an Adrenergic Receptor that causes the contraction of smooth muscle and increases intracellular calcium. Expression of the alpha 1d-adrenoceptor has been reported primarily in smooth muscle of arterioles, eye, gut, skin, vein, as well as in other cell types (e.g. salivary gland). Adrenoceptors are also expressed in hippocampus, cerebral cortex, and brainstem. Caution: The name ADRA1A has been used to describe both the alpha 1d adrenoceptor (human chromosome 20) and the alpha 1c adrenoceptor (human chromosome 8), and the alpha 1c adrenoceptor is also known as alpha 1a adrenoceptor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for alpha-1D Adrenergic R/ADRA1D Antibody (NLS12)(2)

Publications using NLS12

• Karabacak OR, Yilmazer D, Ozturk U et al. The presence and distribution of alpha adrenergic receptors in human renal pelvis and calyces. Urolithiasis. 2013 Oct [PMID: 23877383]
  
  Details:
  Antibodies cited: ADRA 1A (IMG-71129), ADRA1B (IMG-71127) and ADRA 1D (IMG-71130).
• Karabacakb Or, Sener Nc, Yilmazer D. Alpha Adrenergic Receptors In Renal Pelvis And Calyces: Can Rat Models Be Used? Int Braz J et al. 2014 May 14 (IHC-P, Rat, Human)
  
  Details:
  alpha-1D Adrenergic R/ADRA1D antibody used for IHC-P on renal cell carcinoma (RCC) tissues obtained from Human patients undergoing radical nephrectomy, and on Rat's renal pelvis and calyces - 10% neutral formaldehyde solution fixation, 5um paraffin sections, primary used at 1:100 dilution, cytoplasmic staining of receptor concentration (Figure 1).

Bioinformatics

• Gene Symbol: ADRA1D
• Entrez:
  • 146(Human)
  • 11550(Mouse)
  • 29413(Rat)
• Uniprot:
  • P25100(Human)