alpha-1B Adrenergic R/ADRA1B Antibody - BSA Free Summary
Description |
Product can be stored undiluted at 4C for up to 1 month. |
Immunogen |
Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human alpha-1B Adrenergic R/ADRA1B. |
Epitope |
1st cytoplasmic domain |
Specificity |
Human ADRA1B. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SLC22A3 (50%). |
Predicted Species |
Primate (100%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
ADRA1B |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry
- Immunohistochemistry-Paraffin 6 ug/ml
|
Application Notes |
. |
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (100%), Monkey (88%), Mouse (88%), Rat (88%), Hamster (88%), Elephant (88%), Canine (88%).
Packaging, Storage & Formulations
Storage |
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
0.1% Sodium Azide |
Concentration |
1.0 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for alpha-1B Adrenergic R/ADRA1B Antibody - BSA Free
Background
The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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FAQs for alpha-1B Adrenergic R/ADRA1B Antibody (NLS698) (0)
Secondary Antibodies
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