alpha-1B Adrenergic R/ADRA1B Antibody

Images

 
Immunohistochemistry-Paraffin: alpha-1B Adrenergic R/ADRA1B Antibody [NLS698] - Anti-ADRA1B antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced ...read more
Immunohistochemistry-Paraffin: alpha-1B Adrenergic R/ADRA1B Antibody [NLS698] - Medullary Collecting Duct
Immunohistochemistry-Paraffin: alpha-1B Adrenergic R/ADRA1B Antibody [NLS698] - Analysis of anti-ADRA1B antibody with human breast, carcinoma.
Immunohistochemistry-Paraffin: alpha-1B Adrenergic R/ADRA1B Antibody [NLS698] - Anti-ADRA1B antibody IHC of human kidney, collecting duct. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after ...read more

Product Details

Summary
Reactivity Hu, BvSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

alpha-1B Adrenergic R/ADRA1B Antibody Summary

Immunogen
Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human ADRA1B.
Specificity
Human ADRA1B. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SLC22A3 (50%).
Predicted Species
Bovine (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ADRA1B
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 3 ug/ml to 16 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Marmoset (100%), Monkey (88%), Mouse (88%), Rat (88%), Hamster (88%), Elephant (88%), Canine (88%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for alpha-1B Adrenergic R/ADRA1B Antibody

  • a-1B AdrenergicR
  • ADRA1
  • ADRA1B
  • adrenergic, alpha-1B-, receptor
  • alpha-1B Adrenergic R
  • alpha-1B adrenergic receptor
  • alpha1B AdrenergicR
  • Alpha-1B adrenoceptor
  • Alpha-1B adrenoreceptor
  • alpha-1B-adrenergic receptor
  • ALPHA1BAR

Background

The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol ADRA1B
Entrez