Species: Hu, Mu, Rt, Bv, Ca, Ha, Pm, Pm
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: CyTOF-ready, Flow
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Po, Bv, Ca
Applications: WB, ELISA
Host: Goat Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
147 |
Alternate Names |
- ADRA1
- adrenergic, alpha-1B-, receptor
- alpha-1B adrenergic receptor
- Alpha-1B adrenoceptor
- Alpha-1B adrenoreceptor
- alpha-1B-adrenergic receptor
- ALPHA1BAR
|
Research Areas for alpha-1B Adrenergic R/ADRA1B
Find related products by research area and learn more about each of the different research areas below.
GPCRNeuroscience