Gorilla, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (90%), Bat (85%), Opossum (80%), Platypus (80%).
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.1% Sodium Azide
Immunogen affinity purified
Alternate Names for alpha-1B Adrenergic R/ADRA1B Antibody
adrenergic, alpha-1B-, receptor
alpha-1B Adrenergic R
alpha-1B adrenergic receptor
The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Karabacakb Or, Sener Nc, Yilmazer D. Alpha Adrenergic Receptors In Renal Pelvis And Calyces: Can Rat Models Be Used? Int Braz J et al. 2014 May 14 (IHC-P, Rat, Human)
Details: alpha-1B Adrenergic R/ADRA1B antibody used for IHC-P on renal cell carcinoma (RCC) tissues obtained from Human patients undergoing radical nephrectomy, and on Rat's renal pelvis and calyces - 10% neutral formaldehyde solution fixation, 5um paraffin sections, primary used at 1:100 dilution, cytoplasmic staining of receptor concentration (Figure 1).
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