Alpha 1 Fetoprotein Receptor Antibody (5E1)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clone
5E1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Alpha 1 Fetoprotein Receptor Antibody (5E1) Summary

Immunogen
Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with purified human AFP receptor.
Specificity
No reactivity with human IgG.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Western Blot
Application Notes
Detection of AFP receptor in tissue extracts.

Reactivity Notes

Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS, pH 7.4
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for Alpha 1 Fetoprotein Receptor Antibody (5E1)

  • Alpha-1-fetoprotein
  • alpha-fetoglobulin
  • alpha-fetoprotein
  • FETA
  • HP
  • HPAFP

Background

Alpha 1 Fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Expression has been documented in human adrenal, liver, ovary, testis, and pancreas. ESTs have been isolated from normal human brain, liver/spleen, embryo and uterus tissue libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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