Alpha 1 Fetoprotein Receptor Antibody (5E1) - BSA Free

• Reactivity: Hu
• Applications: WB, IHC
• Clone: 5E1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

Alpha 1 Fetoprotein Receptor Antibody (5E1) - BSA Free Summary

• Description: Novus Biologicals Mouse Alpha 1 Fetoprotein Receptor Antibody (5E1) - BSA Free (NBP2-78787) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with purified human AFP receptor.
• Specificity: No reactivity with human IgG.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Detection of AFP receptor in tissue extracts.

Reactivity Notes

Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS, pH 7.4
• Preservative: 0.09% Sodium Azide
• Purity: Protein A purified

Alternate Names for Alpha 1 Fetoprotein Receptor Antibody (5E1) - BSA Free

• Alpha-1-fetoprotein
• alpha-fetoglobulin
• alpha-fetoprotein
• FETA
• HP
• HPAFP

Background

Alpha 1 Fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Expression has been documented in human adrenal, liver, ovary, testis, and pancreas. ESTs have been isolated from normal human brain, liver/spleen, embryo and uterus tissue libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.