ALK-1 Antibody (117720) [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: WB
• Clone: 117720
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 450 SE

ALK-1 Antibody (117720) [mFluor Violet 450 SE] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human ALK‑1
  Asp22-Gln118
  Accession # P37023
• Specificity: Detects human ALK-1 in direct ELISAs and Western blots. Shows less than 1% cross‑reactivity with recombinant mouse ALK-1, recombinant human (rh) Activin RIA, or rhActivin RIB.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: ACVRL1
• Purity: Protein A or G purified from ascites

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from ascites

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ALK-1 Antibody (117720) [mFluor Violet 450 SE]

• activin A receptor type II-like 1
• activin A receptor, type II-like kinase 1
• Activin receptor-like kinase 1
• ACVRL1
• ACVRLK1ORW2
• ALK1
• ALK-1
• ALK1TGF-B superfamily receptor type I
• EC 2.7.11
• HHT
• HHT2EC 2.7.11.30
• serine/threonine-protein kinase receptor R3
• SKR3
• TSR-I

Background

LTK, ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the insulin receptor subfamily of kinases. LTK (leukocyte tyrosine kinase) is expressed in murine B lymphocyte precursors and has also been found in forebrain neurons. ALK (anaplastic lymphoma kinase) is normally highly expressed, specifically in the nervous system. A truncated form containing the catalytic domian of ALK is expressed as the result of a translocation occurring in many non-Hodgkin's lymphomas. The c-Ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ACVRL1