ALDH6A1 Antibody

Western Blot: ALDH6A1 Antibody [NBP2-15341] - Sample (30 ug of whole cell lysate) A: Jurkat 7.5% SDS PAGE; antibody diluted at 1:1000.

Immunohistochemistry-Paraffin: ALDH6A1 Antibody [NBP2-15341] - Paraffin-embedded Breast ca, using antibody at 1:250 dilution.

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

ALDH6A1 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human ALDH6A1. The exact sequence is proprietary.
• Localization: Mitochondrion
• Predicted Species: Mouse (93%), Rat (93%), Bovine (91%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ALDH6A1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 58 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol, 1% BSA
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for ALDH6A1 Antibody

• aldehyde dehydrogenase 6 family, member A1
• Aldehyde dehydrogenase family 6 member A1
• EC 1.2.1.18
• EC 1.2.1.27
• Malonate-semialdehyde dehydrogenase [acylating]
• malonate-semialdehyde dehydrogenase
• methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial
• MGC40271
• MMSADHA
• MMSDHmitochondrial acylating methylmalonate-semialdehyde dehydrogenase

Background

This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: ALDH6A1
• Uniprot:
  • Q02252(Human)