ALDH6A1 Products

Description

ALDH6A1 belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.

Bioinformatics

Entrez	104776 Mouse 4329 Human 81708 Rat
Uniprot	AAH32371 Human NM_005589 Human NP_005580 Human NP_005580.1 Human Q02252 Human
Product By Gene ID	4329
Alternate Names	aldehyde dehydrogenase 6 family, member A1 Aldehyde dehydrogenase family 6 member A1 EC 1.2.1.18 EC 1.2.1.27 Malonate-semialdehyde dehydrogenase [acylating] malonate-semialdehyde dehydrogenase methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial MGC40271 MMSADHA MMSDHmitochondrial acylating methylmalonate-semialdehyde dehydrogenase