Alas1 Antibody (2D5)

Product Discontinued

Alas1 Antibody (2D5) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: ALAS1 (NP_000679, 1 a.a. - 98 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MESVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKETPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLP
• Specificity: ALAS1 - aminolevulinate, delta-, synthase 1 (2D5)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ALAS1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Alas1 Antibody (2D5)

• 5-aminolevulinic acid synthase 1
• ALAS
• ALAS3
• ALASH
• ALAS-H
• aminolevulinate, delta-, synthase 1
• Delta-ALA synthase 1,5-aminolevulinate synthase, nonspecific, mitochondrial
• Delta-aminolevulinate synthase 1
• EC 2.3.1
• EC 2.3.1.37
• MIG4
• migration-inducing protein 4

Background

Delta-aminolevulinate synthase (ALAS; EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2 (MIM 301300).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ALAS1
• Entrez:
  • 211(Human)
• Uniprot:
  • NP_000679(Human)