AIPL1 Antibody - BSA Free

Western Blot: Rabbit Polyclonal AIPL1 Antibody [NBP1-76953] - Western blot analysis of Aipl1 in human brain tissue lysate with Aipl1 antibody at (A) 1 and (B) 2 ug/mL

Immunocytochemistry/ Immunofluorescence: AIPL1 Antibody - BSA Free [NBP1-76953] - Immunofluorescence of aipl1 in human brain tissue with aipl1 antibody at 20 ug/mL.

Immunohistochemistry: AIPL1 Antibody - BSA Free [NBP1-76953] - Immunohistochemistry of AIPL1 in human brain tissue with AIPL1 antibody at 2.5 ug/mL.

• Reactivity: Hu, Mu
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

AIPL1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit AIPL1 Antibody - BSA Free (NBP1-76953) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human Aipl1. The immunogen is located within amino acids 290 - 340 of Aipl1. Amino Acid Squence: RLLENRMAEKQEEERLR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: AIPL1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 1-2 ug/ml
• Control Peptide:

  AIPL1 Peptide (NBP1-76953PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for AIPL1 Antibody - BSA Free

• AIPL2
• aryl hydrocarbon receptor interacting protein-like 1
• aryl hydrocarbon receptor-interacting protein-like 1
• aryl-hydrocarbon-interacting protein-like 1
• LCA4

Background

Aipl1 was initially identified as a protein implicated in Leber congenital amaurosis (LCA), an autosomal recessive disorder thought to be caused by the abnormal development of photoreceptors. Aipl1 is a tetratricopeptide repeat protein that is highly homologous to ARA9, a protein involved in the HSP90-mediated nuclear translocation and transactivation of the aryl hydrocarbon receptor. Aipl1 has also been found to function as part of a chaperone heterocomplex, interacting with Hsp90 and Hsp70. Aipl1 also associates with the cell cycle regulator NUB1. It is thought that Aipl1 cooperates with Hsp70 but not Hsp90 to suppress the formation of NUB1 inclusions, and these interactions are necessary in the normal photoreceptor maturation, as mutations that lead to LCA also compromise the interactions with the Hsp chaperones. At least three isoforms of Aipl1 are known to exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for AIPL1 Antibody (NBP1-76953). (Showing 1 - 1 of 1 FAQ).

1. For my project I'm interested in an primary antibody that is not currently available on the market. The protein I'm interested in is aryl hydrocarbon receptor interacting protein. I would like to use the antibody for Western Blot and/or Immunoprecipitation, and this antibody has to be specific for a zebra fish protein. I would like to ask for a price quote.
   • We currently have no AIPL1 antibodies validated in Zebra fish. If you are interested in testing in Zebra fish, you would qualify for our Innovators Reward Program. You may also contact us at innovators@novusbio.com should you have any questions about the Innovators Reward Program.

Bioinformatics

• Gene Symbol: AIPL1
• Uniprot:
  • NP_055151(Human)