AICL/CLEC-2B Antibody

Immunohistochemistry: AICL Antibody [NBP1-90204] - Staining of human lymph node shows strong cytoplasmic positivity in lymphoid cells outside reaction centra.

Product Discontinued

AICL/CLEC-2B Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: LCPYDWIGFQNKCYYFSKEEGDWNSSKYNCSTQHADLTIIDNIEEMNFLRRYKCSSDHWIGLKMAKNRTGQWVDGATFTKSFGMRGSEGCAYLSDDGAATARCYTERKWICRKR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CLEC2B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for AICL/CLEC-2B Antibody

• Activation-induced C-type lectin
• AICL
• AICLC-type lectin superfamily member 2
• CLEC2B
• CLEC-2B
• CLECSF2
• CLECSF2IFN-alpha-2b-inducing-related protein 1
• C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 2 (activation-induced)
• C-type lectin domain family 2 member B
• C-type lectin domain family 2, member B
• HP10085
• IFN-alpha2b-inducing related protein 1
• IFNRG1

Background

AICL, also known as CLEC2B, is a member of the C-type lectin/C-type lectin-like domain superfamily that shares a common protein fold. The superfamily has a variety of functions including cell adhesion, glycoprotein turnover and cell-cell signaling. Disease research is currently being studied with relation to AICL and hepatitis, botulism, methylmalonic aciduria and sarcoma. This protein is known to have interactions with NINL.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CLEC2B
• Entrez:
  • 9976(Human)