AFAP Antibody (16F50) - Azide and BSA Free

Product Discontinued

AFAP Antibody (16F50) - Azide and BSA Free Summary

• Immunogen: Human recombinant AFAP
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: AFAP1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • ELISA 1:1000-1:2000
  • Flow Cytometry 1:10-1:20
• Application Notes: This antibody is Cytof ready.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Alternate Names for AFAP Antibody (16F50) - Azide and BSA Free

• actin filament associated protein 1
• AFAP
• AFAP1
• AFAP-110
• FLJ56849

Background

AFAP, or Actin filament-associated protein 1, contains a 81 kDa and a 90 kDa isoform, and is involved in the manipulation of actin filaments to form network or bundle structures and the regulation of cell-matrix linkage. Disease research is currently being conducted with AFAP and its relation to familial adenomatous polyposis, adenocarcinoma, breast cancer, prostate adenocarcinoma, prostatitis, polyposis, prostate cancer, and carcinoma. This protein interacts with PRKCB, PRKCD, PRKCG, ACTC1, and PRKCZ during the processes of signal transduction regulation and mechanical stimulus response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for AFAP Antibody (NBP2-22004)(1)

Publication using NBP2-22004

• Chan JS, Tan MJ, Sng MK et al. Cancer-associated fibroblasts enact field cancerization by promoting extratumoral oxidative stress Cell Death Dis Jan 19 2017 [PMID: 28102840] (FLOW, Human). Cell Death Dis. 2017-01-19 [PMID: 28102840] (FLOW, Human)
  
  Details:
  This citation used the PE version of this antibody.

Bioinformatics

• Gene Symbol: AFAP1
• Uniprot:
  • Q12884()