Afamin Antibody [Alexa Fluor® 488]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor 488

Afamin Antibody [Alexa Fluor® 488] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Afamin
  Leu22-Met608
  Accession # O89020
• Specificity: Detects mouse Afamin in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human Afamin is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Afamin Antibody [Alexa Fluor® 488]

• Afamin
• AFM
• ALB2
• ALB2alpha-Alb
• ALBA
• ALBAalpha-albumin
• ALF
• Alpha-Alb
• Alpha-albumin
• MGC125338
• MGC125339

Background

Afamin, also known as AFM or alpha -Albumin, is an 84-88 kDa secreted monomeric glycoprotein member of the Alb/albumin family of molecules. Expressed by hepatocytes, CNS endothelial cells and osteoclasts, Afamin circulates in the blood at low μg/mL concentrations. Afamin is known to bind and transport vitamin E, particularly under conditions where lipoprotein is limited. This is likely to be important in follicular fluid and CSF. Afamin also serves as an osteoclast-derived chemoattractant for preosteoblasts, providing a rationale for the observation that bone formation often follows bone resorption. Mature mouse Afamin is 587 amino acids (aa) in length (aa 22-608). It contains three consecutive albumin domains (aa 22-210, 211-403 and 404-599) that contain characteristic 5 or 6 intrachain disulfide bonds. Full-length mouse Afamin shares 67% aa sequence identity with human Afamin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.