A33/GPA33 Antibody (402104) [Alexa Fluor™ Plus 405]

• Reactivity: Hu
• Clone: 402104
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor Plus 405

A33/GPA33 Antibody (402104) [Alexa Fluor™ Plus 405] Summary

• Specificity: Detects human A33 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse A33 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for A33/GPA33 Antibody (402104) [Alexa Fluor™ Plus 405]

• A33
• cell surface A33 antigen
• glycoprotein A33 (transmembrane)
• Glycoprotein A33
• GPA33
• MGC129986
• MGC129987
• transmembrane glycoprotein A33

Background

Human A33, also known as GPA33, is a 43 kDa type I transmembrane glycoprotein that belongs to the CTX (cortical thymocyte marker in Xenopus) family of cell adhesion molecules within the immunoglobulin superfamily. Other family members include CXADR, ESAM, BT-IgSF, CD2 and JAM-A-C. The extracellular domain (ECD) of human A33 is 214 amino acids (aa) in length and contains one V-type and one C2-type Ig-like domain. This ECD is 80%, 74% and 71% aa identical to canine, bovine and mouse A33 ECD, respectively. A33 is likely to be involved in cell-cell adhesion between epithelial cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.