5-HT1E Antibody - BSA Free

Immunohistochemistry-Paraffin: 5-HT1E Antibody [NBP3-14525] - Immunohistochemistry of formalin-fixed, paraffin-embedded human testis after heat-induced antigen retrieval.

• Reactivity: Hu, Av, Bt, Bv, Pm, Eq, Gp, Pm, Ma-Op, Pm-Or, Pm
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

5-HT1E Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human 5HT1E.
• Epitope: Cytoplasmic Domain
• Specificity: Human 5-HT1E. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Monkey (100%), Primate (100%), Equine (100%), Bat (100%), Avian (94%), Opossum (94%), Orangutan (100%), Guinea Pig (100%), Bovine (100%), Chimpanzee (100%). Backed by our 100% Guarantee.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HTR1E
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: .

Reactivity Notes

Expected reactivity based on percent sequence identity: Lizard (88%)

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for 5-HT1E Antibody - BSA Free

• 5HT1E
• 5-HT1E
• 5-HT-1E
• 5-hydroxytryptamine (serotonin) receptor 1E
• HTR1E
• S31
• S31,5-HT1E5-hydroxytryptamine receptor 1E
• Serotonin receptor 1E

Background

5HT1E Receptor, also known as 5-hydroxytryptamine receptor 1E, is a 365 amino acid protein that is 42 kDa, belongs to the G-protein coupled receptor 1 family, has cell membrane intracellular location; commonly found in the cortex, caudate putamen, claustrum, hippocampus, and amygdala; is one of the many different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that plays a role of a neurotransmitter, a hormone, and a mitogen; this receptor activity is mediated by G proteins that inhibit adenylate cyclase activity. The protein is being studied for its involvement in attention deficit hyperactivity disorder, autism spectrum disorder, chronic fatigue syndrome, hermaphroditism, pharyngitis, neuronitis, and skin papilloma. This protein has been linked to the GPCR downstream signaling, GPCR ligand binding, class A/1 (Rhodopsin-like receptors), serotonin receptors, amine ligand-binding receptors, intracellular calcium signaling, signal transduction, G alpha (i) signaling events, neuroactive ligand-receptor interaction, and amine ligand-binding receptors pathways where it interacts with PSMC3, PSMC4, ADORA3, ADORA1, ADRA2A, APP, CCR3 and over 100 other proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HTR1E