| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | 210-TA-02M/CF | |||
| Carrier Free | 210-TA-020/CF | |||
| Carrier Free | 210-TA-100/CF | |||
| Carrier Free | 210-TA-005/CF | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | 416-ML-010/CF | |||
| Carrier Free | 416-ML-050/CF | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | 404-ML-010/CF | |||
| Carrier Free | 404-ML-050/CF | |||
| Carrier Free | 404-ML-025/CF | |||
| Carrier Free | 404-ML-100/CF | |||
| Carrier Free | 404-ML-01M/CF | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | 404-ML-050/CF | |||
| Carrier Free | 404-ML-025/CF | |||
| Carrier Free | 404-ML-100/CF | |||
| Carrier Free | 404-ML-01M/CF | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | 204-IL-010/CF | |||
| Carrier Free | 204-IL-050/CF | |||
| Carrier Free | 204-IL-001MG/CF | |||
| Carrier Free | 204-IL-020/CF | |||
| Carrier Free | 204-IL-100/CF | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | AF276-SP | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | 410-MT-010/CF | |||
| Carrier Free | 410-MT-050/CF | |||
| Carrier Free | 410-MT-025/CF | |||
| Carrier Free | 410-MT-100/CF | |||
| Carrier Free | 410-MT-01M/CF | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | 401-ML-005/CF | |||
| Carrier Free | 401-ML-025/CF | |||
| Carrier Free | 401-ML-010/CF | |||
| Carrier Free | 401-ML-100/CF | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | AF527-SP | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | AF2480-SP | |||
![C. albicans induces c-Met, EGFR, and E-cadherin to form a multiprotein complex.(A-C) Proximity ligation assay showing the interaction of c-Met with E-cadherin, EGFR with E-cadherin, and c-Met with EGFR in oral epithelial cells with and without 20-min infection with C. albicans. Confocal microscopic images (A). Scale bar 10 μm. Signal counts (B). Proximity ligation assay showing the interaction of c-Met with E-cadherin, EGFR with E-cadherin, and c-Met with EGFR in oral epithelial cells with and without 20-min infection with C. albicans. (A) Confocal microscopic images. Scale bar 10 μm. (B) Signal counts. (C-E) Co-immunoprecipitation experiments in oral epithelial cells transfected with control or E-cadherin (E-cad) siRNA and then infected with C. albicans for 20 min. (C) Representative immunoblots of proteins obtained by immunoprecipitation with an anti-c-Met antibody. (D and E) Densitometric analysis of 5 immunoblots. Results are mean ± SD. **p < 0.01, ***p < 0.001, ****p < 0.0001, ns; not significant (two-tailed Student’s t test [B] or one-way ANOVA with Sidak’s multiple comparisons test [D and E]). Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/37611070), licensed under a CC-BY license. Not internally tested by R&D Systems.](http://images.novusbio.com/fullsize/af276_human-hgf-r-c-met-affinity-purified-polyclonal-ab-8120255561322.jpg)
![Functional interactions among c-Met, EGFR, and E-cadherin during the endocytosis of C. albicans.(A-C) Immunoblot analysis showing the effects of the EGFR inhibitor gefitinib and the c-Met inhibitor SGX523 on C. albicans-induced phosphorylation of c-Met and EGFR in oral epithelial cells after 20 min of infection. Representative immunoblot (A), densitometric analysis of 4 immunoblots showing the phosphorylation of EGFR (B) and c-Met (C). Data are mean ± SD. (D) Effects of SGX523 and gefitinib on the endocytosis of C. albicans by oral epithelial cells. (E and F) Endocytosis of C. albicans by NIH/3T3 cells that expressed human c-Met (E) or human c-Met, EGFR, and HER2 (F). (G) Confocal micrographs of NIH3T3 cells expressing no human receptors (control), human c-Met, human EGFR and HER2, or human c-Met, EGFR, and HER2. The cells were infected with wild-type C. albicans germ tubes for 20 min, after which phosphorylated c-Met was detected with a phosphospecific anti-c-Met antibody. Scale bar 10 μm. Results in (D-F) are the mean ± SD of three experiments, each performed in triplicate. *p < 05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns; not significant (one-way ANOVA with Sidak’s multiple comparisons test [B-D] or two-tailed Student’s t test [E and F]). Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/37611070), licensed under a CC-BY license. Not internally tested by R&D Systems.](http://images.novusbio.com/fullsize/af276_human-hgf-r-c-met-affinity-purified-polyclonal-ab-812025555319.jpg)
![C. albicans activates c-Met in oral epithelial cells.(A) Confocal microscopic images of OKF6/TERT-2 oral epithelial cells infected with C. albicans SC5314 for 20 min. c-Met, the epidermal growth factor receptor (EGFR), and E-cadherin were detected by indirect immunofluorescence using specific antibodies. Arrows point to the organisms in the magnified insets. Scale bar 10 μm. (B and C) Immunoblot analysis showing the time course of the phosphorylation of c-Met and EGFR in oral epithelial cells induced by C. albicans germ tubes (B). Densitometric analysis of 4 immunoblots (C). Data are mean ± SD. (D and E) Knockdown of c-Met with siRNA (D) or inhibition of c-Met signaling with SG523 (E) in oral epithelial cells inhibits the endocytosis of C. albicans. (F) Stimulation of oral epithelial cells with recombinant hepatocyte growth factor (HGF) enhances the endocytosis of C. albicans. Data in (D-F) are the mean ± SD of three experiments, each performed in triplicate. **p < 0.01, ****p < 0.0001, ns; not significant (two-tailed Student’s t test [D and E] or one-way ANOVA with Sidak’s multiple comparisons test [F]). Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/37611070), licensed under a CC-BY license. Not internally tested by R&D Systems.](http://images.novusbio.com/fullsize/af276_human-hgf-r-c-met-affinity-purified-polyclonal-ab-812025555349.jpg)
![N/A HGFR/c-MET [Biotin]](http://images.novusbio.com/fullsize2/DATA_HGF_R_DY358_ELISA_1960.jpg "N/A HGFR/c-MET [Biotin]")