p62/SQSTM1 Products

Antibodies
p62/SQSTM1 Antibody
p62/SQSTM1 Antibody
NBP1-48320
Species: Hu, Mu, Rt, Bovine, Canine, Porcine, Sheep, Invertebrate, Chinese Hamster
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
p62/SQSTM1 Antibody (2C11)
p62/SQSTM1 Antibody (2C11)
H00008878-M01
Species: Hu, Mu, Rt, Dr, Rb
Applications: WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Host: Mouse Monoclonal
Lysates
p62/SQSTM1 Overexpression Lys ...
p62/SQSTM1 Overexpression Lysate (...
H00008878-T01
Species: Hu
Applications: WB
Host: Human
p62/SQSTM1 Overexpression Lys ...
p62/SQSTM1 Overexpression Lysate (...
NBL1-16446
Applications: WB
Proteins
p62/SQSTM1 Partial Protein
p62/SQSTM1 Partial Protein
NBP1-42822PEP
Species: Hu
p62/SQSTM1 Peptide
p62/SQSTM1 Peptide
NBP1-42821PEP
Species: Hu
p62/SQSTM1 Recombinant Protei ...
p62/SQSTM1 Recombinant Protein
H00008878-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
p62/SQSTM1 RNAi
p62/SQSTM1 RNAi
H00008878-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

SQSTM1, also known as p62, encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. SQSTM1 functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for SQSTM1. Mutations in SQSTM1 result in sporadic and familial Paget disease of bone.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Mouse
Rat
Product By Gene ID 8878
Alternate Names
  • P62
  • OSIL
  • ORCA
  • EBIAP
  • sequestosome-1
  • Ubiquitin-binding protein p62
  • phosphotyrosine independent ligand for the Lck SH2 domain p62
  • Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa
  • EBI3-associated protein p60
  • p62B
  • ZIP3
  • p62
  • oxidative stress induced like
  • Paget disease of bone 3
  • A170
  • p60PDB3
  • EBI3-associated protein of 60 kDa
  • sequestosome 1

Research Areas for p62/SQSTM1

Find related products by research area and learn more about each of the different research areas below.

Autophagy
Signal Transduction

PTMs for p62/SQSTM1

Learn more about PTMs related to p62/SQSTM1.

Ubiquitination
Phosphorylation
Cleavage
Acetylation
Methylation
Ribosylation
Deamidation

Bioinformatics Tool for p62/SQSTM1

Discover related pathways, diseases and genes to p62/SQSTM1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related p62/SQSTM1 Blog Posts

Check out the latest blog posts on p62/SQSTM1.
ATG4C - A regulator of the early steps of autophagosome assembly
Autophagy is an important cellular process that maintains homeostasis by degrading and recycling damaged proteins and organelles. Autophagy receptors, such as p62/SQSTM1, recognize these intracellular cargo and mediate their engulfment by the doubl...    Read more.
p62/SQSTM1 - targeting ubiquitinated proteins for autophagic degradation
During autophagy ubiquitinated cargo or substrates are engulfed in a double-membrane autophagosome and transported to the lysosome for degradation. This process is important for maintaining cellular homeostasis and for degrading damaged organelles...    Read more.
LC3/LC3B - measuring autophagosome formation and autophagic flux
Microtubule-associated protein-1 light chain 3 (LC3/LC3B) is a ubiquitin-like protein involved in the formation of the autophagosome. It is homologous to the yeast Atg8 protein. Autophagosomes are important for the degradation and recycling of intr...    Read more.
p62/SQSTM1 (sequestosome 1)
p62/SQSTM1 (sequestosome 1) is ubiquitously-expressed cytoplasmic/adaptor protein. SQSTM1 functions as a signaling hub for various signal transduction pathways involved in apoptosis, cell differentiation, apoptosis, immune response, and K+ channel reg...    Read more.
Read more p62/SQSTM1 related blogs.