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Description

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq].

Bioinformatics

Entrez	9817 Human
Product By Gene ID	9817
Alternate Names	INrf2 INrf2MGC9454 Keap1 kelch-like ECH-associated protein 1 Kelch-like protein 19 KIAA0132MGC4407 KLHL19Cytosolic inhibitor of Nrf2 MGC10630 MGC1114 MGC20887

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Stem Cell Markers

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