ATG16L1 Products

Description

Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy (Mizushima et al., 2003 [PubMed 12665549]).[supplied by OMIM]

Bioinformatics

Product By Gene ID	55054
Alternate Names	APG16 autophagy 16-like (S. cerevisiae) APG16L beta APG16LFLJ10828 APG16-like 1 ATG16 autophagy related 16-like (S. cerevisiae) ATG16 autophagy related 16-like 1 (S. cerevisiae) ATG16A ATG16L autophagy-related protein 16-1 FLJ00045 FLJ10035 FLJ22677 IBD10 WD repeat domain 30 WDR30

Research Areas for ATG16L1

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Autophagy

Related ATG16L1 Blog Posts

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Liver ASK1 activates autophagy to protect against hepatic fat accumulation, non-alcoholic steatohepatitis and fibrosis By Jamshed Arslan, Pharm. D., PhD. The most common chronic liver disorder worldwide is non-alcoholic fatty liver disease (NAFLD). This obesity-linked disorder can manifest as hepatic fat accumulation (steatosis) wit...    Read more.

ATG16L1 - a key player in the development of the autophagosome Like apoptosis, autophagy is a highly regulated physiologic process that involves cellular degradation and recycling of organelles and macromolecules. Autophagy is a survival mechanism induced by states of stress, starvation, and infection. A do...    Read more.

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