Novus Biologicals Announces New C11orf59 Antibody made using SDIX Genomic Antibody Technologyâ„¢

Novus Biologicals announced today a new C11orf59 antibody (catalog number NBP1-71689) for use in stem cell signaling and cancer research. This C11orf59 antibody was developed using SDIX Genomic Antibody TechnologyTM.

C11orf59, also known as LAMTOR1, is one of three proteins that comprise the TOR Ragulator complex. Specifically, this complex targets mTORC1 to lysosomal surfaces to activate a signaling cascade and promote cell growth. Nearly all effects of C11orf59 are associated with mTORC1 kinase growth promotion, and deregulation of the normal mTOR pathway.

C11orf59 is positively regulated by cellular cholesterol depletion and negatively regulated by cellular cholesterol loading. It is involved in LDL uptake and cholesterol homeostasis. Additionally, C11orf59 and PPAR-alpha work together to control lipid and carbohydrate metabolism in diabetes.

SDIX Genomic Antibody Technologyâ„¢ uses sophisticated bioinformatics and immunization strategies to produce high-quality antibodies that specifically bind to a targeted region of protein in its naturally folded form. The ability of any antibody to recognize a protein’s naturally folded state has the potential to expand an antibody’s utility to high-value applications like sandwich immunoassay, ChIP and flow cytometry.  Learn more about SDIX Genomic Antibodies by reading the SDIX Genomic Antibody FAQ or by downloading the SDIX Genomic Antibody White Paper.

About Novus Biologicals (
Novus Biologicals is a biotechnology company whose mission is to accelerate scientific discovery by developing and marketing unique products in the forefront of science.  Novus Biologicals provides primary antibodies, secondary antibodies, conjugated antibodies, proteins, peptides, isotype and loading controls, RNAi, lysates, stem cell lines and antibody labeling kits to the bioscience community.  All of Novus' products are 100% guaranteed to work in the species and applications listed on the datasheet.  By serving niche and emerging markets, Novus Biologicals has formed and will continue to form ongoing partnerships with leading researchers.

About SDIX (
SDIX is a biotechnology company with a core expertise at creating better antigens, better antibodies and better assays for the pharmaceutical, biotechnology and food safety markets. For over 20 years, SDIX has been a leading immuno-solutions Company, developing results-oriented and innovative antibody-based solutions that enable customers to meet high performance research, diagnostic and commercialization objectives.

In the life science market, SDIX’s technology and capabilities are being used to help discover disease mechanisms, facilitate development of new drugs, and provide antibodies and assays for the diagnosis of disease.  In the food safety market, SDIX continues to expand its footprint as an international supplier of rapid pathogen test technologies that enable more accurate and cost effective results.

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Release Date: 
Wednesday, October 5, 2011 - 06:00