Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
Preservative
No Preservative
Purity
Immunogen affinity purified
Notes
Manufactured by SDIX's proprietary Genomic Antibody Technology. GAT FAQs. These products are available in limited quantities. Please enquire about the availability of this product before purchasing.
Alternate Names for TRAF-4 Antibody
CART1
CART1RING finger protein 83
Cysteine-rich domain associated with RING and Traf domains protein 1
Metastatic lymph node gene 62 protein
MLN 62
MLN62
MLN62cysteine-rich domain associated with ring and TRAF domain
RNF83malignant 62
TNF receptor-associated factor 4
TRAF4
TRAF-4
tumor necrosis receptor-associated factor 4A
Background
This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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