TRAF-4 Products

Antibodies
TRAF-4 Antibody
TRAF-4 Antibody
NB100-56177
Species: Hu, Mu, Rt, Bv, Ze
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
TRAF-4 Antibody
TRAF-4 Antibody
NBP2-33647
Species: Hu, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
TRAF-4 Antibody
TRAF-4 Antibody
AF3279
Species: Hu
Applications: WB
Host: Goat Polyclonal
Lysates
TRAF-4 Overexpression Lysate ...
TRAF-4 Overexpression Lysate (Dena...
H00009618-T01
Species: Hu
Applications: WB
TRAF-4 Overexpression Lysate ...
TRAF-4 Overexpression Lysate (Native)
NBL1-17244
Applications: WB
Proteins
TRAF-4 Partial Recombinant Pr ...
TRAF-4 Partial Recombinant Protein
H00009618-Q01
Species: Hu
Applications: WB, ELISA, PA
TRAF-4 Recombinant Protein
TRAF-4 Recombinant Protein
H00009618-P01
Species: Hu
Applications: WB, ELISA, PA
TRAF-4 Recombinant Protein An ...
TRAF-4 Recombinant Protein Antigen
NBP2-33647PEP
Species: Hu
Applications: AC
RNAi
TRAF-4 RNAi
TRAF-4 RNAi
H00009618-R02
Species: Hu
Applications: RNAi, RNAi SP
TRAF-4 RNAi
TRAF-4 RNAi
H00009618-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 9618
Alternate Names
  • Metastatic lymph node gene 62 protein
  • tumor necrosis receptor-associated factor 4A
  • Cysteine-rich domain associated with RING and Traf domains protein 1
  • RNF83malignant 62
  • MLN62cysteine-rich domain associated with ring and TRAF domain
  • CART1RING finger protein 83
  • MLN 62
  • TNF receptor-associated factor 4

Research Areas for TRAF-4

Find related products by research area and learn more about each of the different research areas below.

Cancer
Zinc Finger

PTMs for TRAF-4

Learn more about PTMs related to TRAF-4.

Phosphorylation
Cleavage
Ubiquitination

Bioinformatics Tool for TRAF-4

Discover related pathways, diseases and genes to TRAF-4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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