Species: Hu, Mu, Rt, Pm, Rb
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Po, Am, Bv, Ca, Ch, ChHa, Eq, Fe, Ha, Pm, Rb, Av, Pm, Pm, Pm-Or, Re
Applications: WB, Simple Western
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, Simple Western, ICC/IF, IHC, KO, Mycoplasma
Host: Rabbit Polyclonal
Species: Mu
Applications: ELISA
Species: Rt
Applications: ELISA
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The S. cerevisiae silent information regulator 2 (Sir2) protein is an NAD+-dependent histone deacetylase (HDACs) that plays a critical role in transcriptional silencing, genome stability, and longevity (1-2). Part of the Sirtuin family (Sir2, Sir3, Sir3), yeast Sir2 is the founding member of Class III HDACs. A human homologue of Sir2 , SIRT1, regulates the activity of the p53 tumor suppressor and inhibits apoptosis (3-4).
Bioinformatics
| Product By Gene ID |
23411 |
| Alternate Names |
- EC 3.5.1
- S. cerevisiae, homolog) 1
- SIR2alpha
- SIR2L1
- SIR2-like protein 1
- SIRT1
- Sirtuin 1
|
