Product Search for TGFB1: Novus Biologicals

7754-BH

Recombinant Human TGF-beta 1 (Human Cell-expressed) Protein

5 μg

7754-BH

7754-BH) inhibits recombinant mouse IL-4 induced proliferation in the HT-2 mouse T cell line. The ED₅₀ for this effect is 0.04-0.2 ng/mL." class="big_lightbox">

7754-BH) inhibits recombinant mouse IL-4 induced proliferation in the HT-2 mouse T cell line. The ED₅₀ for this effect is 0.04-0.2 ng/mL." alt="Recombinant human TGF-beta 1 (7754-BH) inhibits recombinant mouse IL-4 induced proliferation in the HT-2 mouse T cell line. The ED₅₀ for this effect is 0.04-0.2 ng/mL." class="big_thumb" />

Reactivity:

Hu

Species Glossary

Reactivity: Hu

Applications:

Applications:

Available Formulations

Formulation	Catalog #	Availability	Price
Carrier Free	7754-BH-005/CF
Carrier Free	7754-BH-025/CF
Carrier Free	7754-BH-100/CF
Carrier Free	7754-BH-500/CF
Carrier Free	7754-BH-01M/CF

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240-B

Recombinant Human TGF-beta 1 Protein

(912 Publications)

2 μg

240-B

7754-BH) Recombinant Human TGF‑ beta 1 as measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cell. (orange, green, respectively)." class="big_lightbox">

7754-BH) Recombinant Human TGF‑ beta 1 as measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cell. (orange, green, respectively)." alt="Equivalent bioactivity of CHO-derived (Catalog # 240-B) and HEK293-derived (7754-BH) Recombinant Human TGF‑ beta 1 as measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cell. (orange, green, respectively)." class="big_thumb" />

Reactivity:

Hu

Species Glossary

Reactivity: Hu

Applications:

Applications:

Available Formulations

Formulation	Catalog #	Availability	Price
Carrier Free	240-B-001MG/CF
Carrier Free	240-B-002/CF
Carrier Free	240-B-010/CF
Carrier Free	240-B-500/CF

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7666-MB

Recombinant Mouse TGF-beta 1 Protein

(394 Publications)

5 μg

7666-MB

7666-MB) inhibits IL-4-dependent proliferation in the HT-2 mouse T cell line. The ED₅₀ for this effect is 0.04-0.2 ng/mL." class="big_lightbox">

7666-MB) inhibits IL-4-dependent proliferation in the HT-2 mouse T cell line. The ED₅₀ for this effect is 0.04-0.2 ng/mL." alt="Recombinant mouse TGF-beta 1 (7666-MB) inhibits IL-4-dependent proliferation in the HT-2 mouse T cell line. The ED₅₀ for this effect is 0.04-0.2 ng/mL." class="big_thumb" />

Reactivity:

Mu

Species Glossary

Reactivity: Mu

Applications:

Applications:

Available Formulations

Formulation	Catalog #	Availability	Price
Carrier Free	7666-MB-005/CF

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DB100C

Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

(456 Publications)

1 Kit

DB100C

Reactivity:

Hu, Mu, Rt, Po, Ca

Species Glossary

Reactivity: Hu, Mu, Rt, Po, Ca

Applications:

Applications:

Conjugate	Catalog #	Availability	Size	Price
HRP	SB100C
HRP	PDB100C

Available Formulations

Formulation	Catalog #	Availability	Price
Carrier Free	SB100C
Carrier Free	PDB100C

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MAB1835

TGF beta 1/2/3 Antibody (1D11) [Unconjugated]

(1 Review)

(228 Publications)

100 μg

MAB1835

240-B) inhibits Recombinant Mouse IL-4 (Catalog # 404-ML) induced proliferation in the HT-2 mouse T cell line in a dose-dependent manner (orange line). Inhibition of Recombinant Mouse IL-4 (7.5 ng/mL) activity elicited by Recombinant Human TGF-beta 1 (1 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-TGF-beta 1, 2, 3 Monoclonal Antibody (Catalog # MAB1835). The ND₅₀ is typically 0.25-1.25 µg/mL." class="big_lightbox">

Recombinant Human TGF-beta 1 (Catalog # <a class=

240-B) inhibits Recombinant Mouse IL-4 (Catalog # 404-ML) induced proliferation in the HT-2 mouse T cell line in a dose-dependent manner (orange line). Inhibition of Recombinant Mouse IL-4 (7.5 ng/mL) activity elicited by Recombinant Human TGF-beta 1 (1 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-TGF-beta 1, 2, 3 Monoclonal Antibody (Catalog # MAB1835). The ND₅₀ is typically 0.25-1.25 µg/mL." alt="Recombinant Human TGF-beta 1 (Catalog # 240-B) inhibits Recombinant Mouse IL-4 (Catalog # 404-ML) induced proliferation in the HT-2 mouse T cell line in a dose-dependent manner (orange line). Inhibition of Recombinant Mouse IL-4 (7.5 ng/mL) activity elicited by Recombinant Human TGF-beta 1 (1 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-TGF-beta 1, 2, 3 Monoclonal Antibody (Catalog # MAB1835). The ND₅₀ is typically 0.25-1.25 µg/mL." class="big_thumb" />

Apoptotic cell-induced immunomodulation in mice with collagen-induced arthritis (CIA) is dependent on transforming growth factor (TGF)-beta . CIA mice that received or did not receive apoptotic cells, with or without anti-TGF-beta blocking antibody were scored daily (a). Data are shown as mean ± SEM of five mice per group from one of two representative experiments; *p < 0.05, **p < 0.01 (Friedman test analysis of variance (ANOVA) with Dunn's multiple comparisons test). Anti-collagen IgG2a antibodies (Ab) were quantified in plasma (b). Data from 5 to 16 mice from two to three independent experiments (no difference, Kruskal-Wallis test ANOVA with Dunn’s multiple comparisons test). Lymph node cells were collected, cultured, and T cell proliferation in response to collagen protein or CD3-specific Ab stimulations was evaluated (c). Data are shown as mean ± SEM from one of two representative experiments; *p < 0.05, **p < 0.01 (nonparametric unpaired t test). Percent and absolute number of Foxp3+ T regulatory cells (Treg) were evaluated in the spleen (d) and suppressive assays were performed by isolating and adding Treg at a different ratio into collagen-specific cultures and responder T cell proliferation was assessed (e). Data are shown as mean ± SEM from one experiment (d Kruskal-Wallis test ANOVA with Dunn’s multiple comparisons test; e Friedman test ANOVA with Dunn’s multiple comparisons test). Plasmacytoid dendritic cells (pDC), conventional dendritic cells (cDC) and macrophages (macro) were isolated and cultured with naïve allogenic T cells to determine Treg polarization (f), and their response to TLR ligand was assessed through evaluation of CD40 costimulatory molecule expression (g). Data from individual mouse plus mean (black bar) from one experiment representative of four are shown; *p < 0.05, ***p < 0.001 (f ordinary one-way ANOVA with Tukey’s multiple comparisons test; g Kruskal-Wallis test ANOVA with Dunn’s multiple comparisons test). BrDU 5-Bromo-2’-deoxyuridine Im

<b>Biological Strategies Validation. </b>TGF beta 1 stimulates the expression of ECM components in human and rabbit primary cells. (A) Selected ECM mRNA transcripts were measured using qRT-PCR in human RPTEC or human IPF134 following 48 hr stimulation with TGF beta 1 (10 ng/mL). Data show transcript abundance relative to the unstimulated control (indicated by the dashed line) and are shown as mean ± SD of four (RPTEC) or seven (IPF134) independent experiments. ****P < 0.0001; ****P < 0.001; **P < 0.01; Student’s t-test. (B) The accumulation of ECM in human RPTEC (i) or human IPF (ii) cells stimulated with 10ng/mL TGF beta 1 was evaluated via measurement of the incorporation of 14C-labelled amino acids into the deposited ECM. Data presented are the mean ± SD of three independent experiments. **P < 0.01; Student’s t-test. (C) Increased mature ECM accumulation following treatment of cells with a pro-fibrotic stimulus can be visualised following in-situ fluorescent staining using the Flamingo dye. Cells from three different systems (primary human RPTEC; primary human IPF134; co-culture of primary rabbit RPTEC with primary rabbit renal fibroblasts) were cultured in the absence (top) or presence (bottom) of 10 ng/ml TGF beta 1 before decellularised matrix was fixed and stained in situ with Flamingo fluorescent dye. Images show a single field. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/28855577), licensed under a CC-BY license. Not internally tested by R&D Systems.

CBirTox induced expression of Foxp3 is dependent on TGF-beta but independent of RA signaling.(A) CD11c+ DCs were isolated from the spleen, MLN or LP and pulsed with 1 μg/ml of CBirTox or CBir1 peptide for 2 hours prior to co-culture with CD4+ CBir1 Tg T cells for 4 days before flow cytometry analysis. Results represent 2–3 independent experiments (B-C) CD11c+ DCs were isolated from the spleen and pulsed with 1 μg/ml of CBirTox for 1 hour before co-culture with CD4+ CBir1 Tg T cells in the presence of 1 μM of the RA inhibitor LE135 or RA for 4 days. Representative flow plots (B) of 3 independent experiments (C) are shown. (D-E) Splenic CD19+ B cells were pulsed with 2 μg of CBirTox for 2 hours before co-culture with with CD4+ CBir1 Tg T cells with or without the presence of 10 μg/ml anti-TGF-beta (1,2,3) for 4 days prior to flow cytometry analysis. Representative flow plots (D) of 4–5 independent experiments (E) are shown. Results of all experiments are expressed as the mean ± SEM. ***p<0.0005, NS, not significant. Groups of three or more were analyzed using one-way ANOVA with Bonferroni’s post test. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/28750075), licensed under a CC-BY license. Not internally tested by R&D Systems.

Expression of genes involved in fibrosis at 6 months.(A) IHC and ISH (inlets) showing MMP9 expression in proliferating myofibroblasts and ductular cells. (B) IHC for TGF beta 1. Contrary to MMP9, TGF beta 1 is expressed only in proliferating ductular cells which are also positive for cytokeratin. (C, D) ISH for PDGFAa and IL1b. Transcripts of both genes are detected in a small subset of proliferating myofibroblasts and ductular cells. (A–C, red arrowheads, ductular cells). Microscopic images are 400×. Bars, 50 µm. Image collected and cropped by CiteAb from the following open publication (//pubmed.ncbi.nlm.nih.gov/22164219), licensed under a CC-BY license. Not internally tested by R&D Systems.

Reactivity:

All-Multi

Species Glossary

Reactivity: All-Multi

Applications:

, ,

Applications: , ,

Host:

Mouse Monoclonal

Host: Mouse Monoclonal

Sizes:

Sample Size Available

Sizes: Sample Size Available

Conjugate:

Unconjugated

Available Conjugates:

Validated by:

Validated by:

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	FAB1835U
Alexa Fluor 405	FAB1835V
Alexa Fluor 488	FAB1835G
Alexa Fluor 532	FAB1835X
Alexa Fluor 594	FAB1835T
Alexa Fluor 647	FAB1835R
Alexa Fluor 700	FAB1835N
Alexa Fluor 750	FAB1835S
Allophycocyanin	FAB1835A
Biotin	FAB1835B
CoraFluor 1	FAB1835CL1
DyLight 350	FAB1835D
DyLight 405	FAB1835E
DyLight 488	FAB1835K
DyLight 550	FAB1835L
DyLight 594	FAB1835M
DyLight 650	FAB1835W
DyLight 680	FAB1835Y
DyLight 755	FAB1835Z
FITC	FAB1835F
HRP	FAB1835H
Janelia Fluor 525	FAB1835JF525
Janelia Fluor 549	FAB1835I
Janelia Fluor 646	FAB1835J
Janelia Fluor 669	FAB1835JF669
PerCP	FAB1835C
mFluor Violet 450 SE	FAB1835MFV450
mFluor Violet 500 SE	FAB1835MFV500
mFluor Violet 610 SE	FAB1835MFV610

Available Formulations

Formulation	Catalog #	Availability	Price
Carrier Free	MAB1835-SP
Carrier Free	MAB1835-500

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DY240

Human TGF-beta 1 DuoSet ELISA, 15 Plate

(210 Publications)

1 Kit (for 5 Plates)

DY240

Reactivity:

Hu

Species Glossary

Reactivity: Hu

Applications:

Applications:

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DY1679

Mouse TGF-beta 1 DuoSet ELISA, 15 Plate

(174 Publications)

1 Kit (for 5 Plates)

DY1679

Reactivity:

Mu

Species Glossary

Reactivity: Mu

Applications:

Applications:

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AB-100-NA

TGF-beta Antibody [Unconjugated] - Pan Specific

(100 Publications)

1 mg

AB-100-NA

VC003). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in epitjhelial cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox">

TGF-beta was detected in immersion fixed paraffin-embedded sections of human prostate tissue using Rabbit Anti-TGF-beta Pan Specific Polyclonal Antibody (Catalog # AB-100-NA) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Rabbit IgG VisUCyte™ HRP Polymer Antibody (Catalog # <a class=

VC003). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in epitjhelial cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." alt="TGF-beta was detected in immersion fixed paraffin-embedded sections of human prostate tissue using Rabbit Anti-TGF-beta Pan Specific Polyclonal Antibody (Catalog # AB-100-NA) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Rabbit IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC003). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in epitjhelial cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_thumb" />

101-B1) inhibits Recombinant Mouse IL-4 (Catalog # 404-ML) induced proliferation in the HT-2 mouse T cell line in a dose-dependent manner (orange line). Inhibition of Recombinant Mouse IL-4 (7.5 ng/mL) activity elicited by Porcine TGF-beta 1 (1 ng/mL) is neutralized (green line) by increasing concentrations of TGF-beta Pan Specific Polyclonal Antibody (Catalog # AB-100-NA). The ND₅₀range is 5-30 µg/mL." class="big_lightbox">

101-B1) inhibits Recombinant Mouse IL-4 (Catalog # 404-ML) induced proliferation in the HT-2 mouse T cell line in a dose-dependent manner (orange line). Inhibition of Recombinant Mouse IL-4 (7.5 ng/mL) activity elicited by Porcine TGF-beta 1 (1 ng/mL) is neutralized (green line) by increasing concentrations of TGF-beta Pan Specific Polyclonal Antibody (Catalog # AB-100-NA). The ND₅₀range is 5-30 µg/mL." class="big_thumb" />

TGF-beta induces IL-9 mRNA expression in Th1 and Th2 cells.Naïve CD4+ T cells were activated with fibroblast-bound anti-CD3/CD28 under classical Th1 and Th2 conditions, with IL-12 and anti-IL-4 or IL-4, anti-IFN-gamma , and anti-IL-12 respectively for 5 days, restimulated at day 5 and split in cultures with and without TGF-beta or anti-TGF-beta for 5 more days of stimulation. (A, C and D) qRT-PCR gene expression analysis of the relative gene expression of IL-9, GATA3, and Tbet at day 10 relative to the Th0 culture. (B) CT value from qRT-PCR gene expression analysis of the gene PU.1. Each donor is represented by a specific symbol and connected with a line. Data are from four independent experiments, each with two donors. *p<0.05, **p<0.01, ***p<0.001. Image collected and cropped by CiteAb from the following open publication (//dx.plos.org/10.1371/journal.pone.0021695), licensed under a CC-BY license. Not internally tested by R&D Systems.

Reactivity:

All-Multi

Species Glossary

Reactivity: All-Multi

Applications:

, ,

Applications: , ,

Host:

Rabbit Polyclonal

Host: Rabbit Polyclonal

Conjugate:

Unconjugated

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AF5626

HIC5/TGFB1I1 Antibody [Unconjugated]

100 μg

AF5626

Western blot shows lysates of MCF-7 human breast cancer cell line and HepG2 human hepatocellular carcinoma cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human HIC5/TGFB1I1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5626) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for HIC5/TGFB1I1 at approximately 50 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

HIC5/TGFB1I1 was detected in immersion fixed PC-3 human prostate cancer cell line, unstimulated (upper panel) or stimulated with 10 ng/mL Recombinant Human BMP-4 (Catalog # 314-BP; lower panel), using Goat Anti-Human HIC5/TGFB1I1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5626) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL001) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm (unstimulated) and nuclei (stimulated). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Reactivity:

Hu

Species Glossary

Reactivity: Hu

Applications:

,

Applications: ,

Host:

Goat Polyclonal

Host: Goat Polyclonal

Sizes:

Sample Size Available

Sizes: Sample Size Available

Conjugate:

Unconjugated

Available Conjugates:

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	AF5626U-100UG
Alexa Fluor 405	AF5626V-100UG
Alexa Fluor 488	AF5626G-100UG
Alexa Fluor 532	AF5626X-100UG
Alexa Fluor 594	AF5626T-100UG
Alexa Fluor 647	AF5626R-100UG
Alexa Fluor 700	AF5626N-100UG
Alexa Fluor 750	AF5626S-100UG
Alexa Fluor Plus 405	AF5626AFP405-100UG
Alexa Fluor Plus 488	AF5626AFP488-100UG
Alexa Fluor Plus 555	AF5626AFP555-100UG
Alexa Fluor Plus 594	AF5626AFP594-100UG
Alexa Fluor Plus 647	AF5626AFP647-100UG
Alexa Fluor Plus 680	AF5626AFP680-100UG
Allophycocyanin	AF5626A
Biotin	AF5626B
CoraFluor 1	AF5626CL1
DyLight 350	AF5626D
DyLight 405	AF5626E
DyLight 488	AF5626K
DyLight 550	AF5626L
DyLight 594	AF5626M
DyLight 650	AF5626W
DyLight 680	AF5626Y
DyLight 755	AF5626Z
FITC	AF5626F
HRP	AF5626H
Janelia Fluor 525	AF5626JF525
Janelia Fluor 549	AF5626I
Janelia Fluor 646	AF5626J
Janelia Fluor 669	AF5626JF669
PE	AF5626P
PerCP	AF5626C
mFluor Violet 450 SE	AF5626MFV450
mFluor Violet 500 SE	AF5626MFV500
mFluor Violet 610 SE	AF5626MFV610

Available Formulations

Formulation	Catalog #	Availability	Price
Carrier Free	AF5626-SP

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AF-246-NA

LAP (TGF-beta 1) Antibody [Unconjugated]

(3 Reviews)

(42 Publications)

100 μg

AF-246-NA

HAF017). A specific band was detected for LAP (TGF-beta 1) at approximately 48 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox">

Western blot shows lysates of Saos-2 human osteosarcoma cell line. PVDF membrane was probed with 2 µg/mL of Goat Anti-Human LAP (TGF-beta 1) Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-246-NA) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

HAF017). A specific band was detected for LAP (TGF-beta 1) at approximately 48 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." alt="Western blot shows lysates of Saos-2 human osteosarcoma cell line. PVDF membrane was probed with 2 µg/mL of Goat Anti-Human LAP (TGF-beta 1) Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-246-NA) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for LAP (TGF-beta 1) at approximately 48 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_thumb" />

NL001) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. Staining was performed using our protocol for Fluorescent ICC Staining of Non-adherent Cells." class="big_lightbox">

LAP (TGF-beta 1) was detected in immersion fixed Human peripheral blood mononuclear cells using Goat Anti-Human LAP (TGF-beta 1) Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-246-NA) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; <a class=

NL001) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. Staining was performed using our protocol for Fluorescent ICC Staining of Non-adherent Cells." class="big_thumb" />

HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system." class="big_lightbox">

Simple Western lane view shows lysates of K562 human chronic myelogenous leukemia cell line and A549 human lung carcinoma cell line, loaded at 0.2 mg/mL. A specific band was detected for LAP (TGF-beta 1) at approximately 61 kDa (as indicated) using 20 µg/mL of Goat Anti-Human LAP (TGF-beta 1) Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-246-NA) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=

HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system." class="big_thumb" />

246-LP) inhibits Recom-binant Human TGF-beta 1 (Catalog # 240-B) growth inhibition activity in the HT-2 mouse T cell line in a dose-dependent manner (orange line). Inhibition of Recom-binant Human TGF-beta 1 (1 ng/mL) activity elicited by Recombin-ant Human LAP TGF-beta 1 (500 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human LAP TGF-beta 1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-246-NA). The ND₅₀ is typically 0.4-2 µg/mL." class="big_lightbox">

Recombinant Human LAP TGF-beta 1 (Catalog # <a class=

246-LP) inhibits Recom-binant Human TGF-beta 1 (Catalog # 240-B) growth inhibition activity in the HT-2 mouse T cell line in a dose-dependent manner (orange line). Inhibition of Recom-binant Human TGF-beta 1 (1 ng/mL) activity elicited by Recombin-ant Human LAP TGF-beta 1 (500 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human LAP TGF-beta 1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF-246-NA). The ND₅₀ is typically 0.4-2 µg/mL." class="big_thumb" />

Reactivity:

Hu

Species Glossary

Reactivity: Hu

Applications:

, , ,

Applications: , , ,

Host:

Goat Polyclonal

Host: Goat Polyclonal

Sizes:

Sample Size Available

Sizes: Sample Size Available

Conjugate:

Unconjugated

Available Conjugates:

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	AF-246-NAU-100UG
Alexa Fluor 405	AF-246-NAV-100UG
Alexa Fluor 488	AF-246-NAG-100UG
Alexa Fluor 532	AF-246-NAX-100UG
Alexa Fluor 594	AF-246-NAT-100UG
Alexa Fluor 647	AF-246-NAR-100UG
Alexa Fluor 700	AF-246-NAN-100UG
Alexa Fluor 750	AF-246-NAS-100UG
Alexa Fluor Plus 405	AF-246-NAAFP405
Alexa Fluor Plus 488	AF-246-NAAFP488
Alexa Fluor Plus 555	AF-246-NAAFP555
Alexa Fluor Plus 594	AF-246-NAAFP594
Alexa Fluor Plus 647	AF-246-NAAFP647
Alexa Fluor Plus 680	AF-246-NAAFP680
Allophycocyanin	AF-246-NAA
Biotin	BAF246
CoraFluor 1	AF-246-NACL1
DyLight 350	AF-246-NAD
DyLight 405	AF-246-NAE
DyLight 488	AF-246-NAK
DyLight 550	AF-246-NAL
DyLight 594	AF-246-NAM
DyLight 650	AF-246-NAW
DyLight 680	AF-246-NAY
DyLight 755	AF-246-NAZ
FITC	AF-246-NAF
HRP	AF-246-NAH
Janelia Fluor 525	AF-246-NAJF525
Janelia Fluor 549	AF-246-NAI
Janelia Fluor 646	AF-246-NAJ
Janelia Fluor 669	AF-246-NAJF669
PE	AF-246-NAP
PerCP	AF-246-NAC
mFluor Violet 450 SE	AF-246-NAMFV450
mFluor Violet 500 SE	AF-246-NAMFV500
mFluor Violet 610 SE	AF-246-NAMFV610

Available Formulations

Formulation	Catalog #	Availability	Price
Carrier Free	AF-246-SP

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H00007041-M01

HIC5/TGFB1I1 Antibody (4B2-D8) - Azide and BSA Free

0.1 mg

H00007041-M01

Western Blot: HIC5/TGFB1I1 Antibody (4B2-D8) [H00007041-M01] - Analysis of TGFB1I1 expression in transfected 293T cell line by TGFB1I1 monoclonal antibody (M01), clone 4B2-D8.Lane 1: TGFB1I1 transfected lysate(47.9 KDa).Lane 2: Non-transfected lysate.

Sandwich ELISA: HIC5/TGFB1I1 Antibody (4B2-D8) [H00007041-M01] - Detection limit for recombinant GST tagged TGFB1I1 is approximately 0.03ng/ml as a capture antibody.

Reactivity:

Hu

Species Glossary

Reactivity: Hu

Applications:

, ,

Applications: , ,

Host:

Mouse Monoclonal

Host: Mouse Monoclonal

Conjugate:

Unconjugated

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NBP2-16828

HIC5/TGFB1I1 Antibody - BSA Free

0.1 ml

NBP2-16828

Non-transfected (-) and transfected (+) 293T whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with HIC5 antibody [N1], N-term (NBP2-16828) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Reactivity:

Hu

Species Glossary

Reactivity: Hu

Applications:

,

Applications: ,

Host:

Rabbit Polyclonal

Host: Rabbit Polyclonal

Conjugate:

Unconjugated

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Category

Protein/Target

Applications

Reactivity

Citation

Antibody Validation

Reviews

Host

Available Conjugates

Format

Modification

Clonality

Clone

Gene Symbol

Images Type

Isotype

Kit Type

Preservative

Protein Or Peptide

Research Areas

Has Sample Size

Promotional Item

Species Glossary

Recombinant Human TGF-beta 1 (Human Cell-expressed) Protein

Recombinant Human TGF-beta 1 Protein

Recombinant Mouse TGF-beta 1 Protein

Human/Mouse/Rat/Porcine/Canine TGF-beta 1 Quantikine ELISA

TGF beta 1/2/3 Antibody (1D11) [Unconjugated]

Human TGF-beta 1 DuoSet ELISA, 15 Plate

Mouse TGF-beta 1 DuoSet ELISA, 15 Plate

TGF-beta Antibody [Unconjugated] - Pan Specific

HIC5/TGFB1I1 Antibody [Unconjugated]

LAP (TGF-beta 1) Antibody [Unconjugated]

HIC5/TGFB1I1 Antibody (4B2-D8) - Azide and BSA Free

HIC5/TGFB1I1 Antibody - BSA Free