| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | 201-LB-005/CF | |||
| Carrier Free | 201-LB-025/CF | |||
| Carrier Free | 201-LB-500/CF | |||
| Carrier Free | 201-LB-100/CF | |||
| Carrier Free | 201-LB-010/CF | |||
| Carrier Free | 201-LB-01M/CF | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | AF-401-SP | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | SMLB00C | |||
| Carrier Free | PMLB00C | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | STA00D | |||
| Carrier Free | PDTA00D | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | 6507-IL-025/CF | |||
| Carrier Free | 6507-IL-100/CF | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | 6507-IL-010/CF | |||
| Carrier Free | 6507-IL-025/CF | |||
| Carrier Free | 6507-IL-100/CF | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | 404-ML-010/CF | |||
| Carrier Free | 404-ML-050/CF | |||
| Carrier Free | 404-ML-025/CF | |||
| Carrier Free | 404-ML-100/CF | |||
| Carrier Free | 404-ML-01M/CF | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | 404-ML-050/CF | |||
| Carrier Free | 404-ML-025/CF | |||
| Carrier Free | 404-ML-100/CF | |||
| Carrier Free | 404-ML-01M/CF | |||
![P. gingivalis and its OMVs differentially induce inflammasome signaling and pyroptosis in murine macrophages. BMM were infected as before (2 h at MOI of 25:1, see Materials and Methods) with viable P. gingivalis (Pg), heat-killed-Pg (HK-Pg), OMVs, or heat-inactivated-OMVs (HI-OMVs) and (A) the activation of inflammasome components in the lysates [or supernatants (sup) where indicated] measured after 24 h by Western blot; beta -actin serves as a loading control throughout. Western blot data are representative of at least three independent experiments. (B) Production of IL-1 beta and IL-18 (by ELISA) from BMM was measured in the supernatant at 24 h. Data are mean ± SD from four independent experiments. Cell viability was determined by measuring extracellular LDH release and by 7-AAD exclusion (by flow-cytometry) at 24 h. 7-AAD is a membrane impermeant dye that is excluded from viable cells. The percent of 7-AAD positive (±SD) cells from three independent experiments was calculated relative to the untreated control. BMM treated with H2O2 (1 mM for 60 min) were included as positive control for 7-AAD. A representative histogram is shown. Cells were also treated where indicated with OMVs in the presence of KYT-1 and KYT-36 (10 μM of each). *p < 0.05. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/28824884), licensed under a CC-BY license. Not internally tested by R&D Systems.](http://images.novusbio.com/fullsize/af-401-na_mouse-il-1-beta-il-1f2-affinity-purified-polyclonal-ab-4120241033831.jpg)
![N/A IL-1 beta/IL-1F2 [Biotin]](http://images.novusbio.com/fullsize2/DATA_IL1_beta_DY401_ELISA_2321.jpg "N/A IL-1 beta/IL-1F2 [Biotin]")
![N/A IL-1 beta/IL-1F2 [HRP]](http://images.novusbio.com/fullsize2/DATA_IL1_beta_MLB00_ELISA_994.jpg "N/A IL-1 beta/IL-1F2 [HRP]")
![N/A IL-1 beta/IL-1F2 [HRP]](http://images.novusbio.com/fullsize2/IL1_beta_MLB00_ELISA_425.jpg)
![N/A IL-19 [HRP]](http://images.novusbio.com/fullsize2/dta00d_human-tnf-alpha-quantikine-pharmpak-50-plates-2672021102137.jpg "N/A IL-19 [HRP]")
![N/A IL-19 [HRP]](http://images.novusbio.com/fullsize2/dta00d_human-tnf-alpha-quantikine-pharmpak-50-plates-2672021102236.jpg)
![N/A IL-1 beta/IL-1F2 [Biotin]](http://images.novusbio.com/fullsize2/DATA_IL1_beta_DY201_ELISA_2384.jpg "N/A IL-1 beta/IL-1F2 [Biotin]")
![N/A IL-1 beta/IL-1F2 [HRP]](http://images.novusbio.com/fullsize2/DATA_IL1_beta_DLB50_ELISA_738.jpg "N/A IL-1 beta/IL-1F2 [HRP]")
![N/A IL-1 beta/IL-1F2 [HRP]](http://images.novusbio.com/fullsize2/DATA_IL1_beta_DLB50_ELISA_739.jpg)
![N/A IL-1 beta/IL-1F2 [HRP]](http://images.novusbio.com/fullsize2/IL-1_beta_DLB50_ELISA_129.jpg)
![N/A CXCL8/IL-8 [Biotin]](http://images.novusbio.com/fullsize2/DATA_IL8_DY208_ELISA_2307.jpg "N/A CXCL8/IL-8 [Biotin]")
