ZNRF2 Antibody (JJ0924)

Immunohistochemistry-Paraffin: ZNRF2 Antibody (JJ0924) [NBP2-67904] - Analysis of paraffin-embedded mouse testis tissue using anti-ZNRF2 antibody. Counter stained with hematoxylin.

Product Discontinued

ZNRF2 Antibody (JJ0924) Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Synthetic peptide within Human ZNRF2 aa 162-206 / 242. (SwissProt: Q8NHG8 Human; SwissProt: Q71FD5 Mouse; Entrez Gene: 362367 Rat)
• Localization: Cell junction, Cell membrane, Cell projection, Endosome, Lysosome, Membrane, Synapse.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: ZNRF2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50-1:200
  • Western Blot 1:1500

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: TBS (pH7.4), 0.05% BSA, 40% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for ZNRF2 Antibody (JJ0924)

• EC 6.3.2.-
• Protein Ells2
• RING finger protein 202
• RNF202E3 ubiquitin-protein ligase ZNRF2
• zinc and ring finger 2
• zinc finger/RING finger 2
• Zinc/RING finger protein 2

Background

Zinc- and RING- finger 2 (ZNRF2) is suggested to play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ZNRF2