ZNF274 Antibody

Product Discontinued

ZNF274 Antibody Summary

• Immunogen: ZNF274 (NP_598009, 420 a.a. ~ 531 a.a) partial recombinant protein with GST tag.QKIDNPESQANSGALDTNQVLLHKIPPRKRLRKRDSQVKSMKHNSRVKIHQKSCERQKAKEGNGCRKTFSRSTKQITFIRIHKGSQVCRCSECGKIFRNPRYFSVHKKIHT
• Specificity: ZNF274 - zinc finger protein 274
• Clonality: Polyclonal
• Host: Mouse
• Gene: ZNF274
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Chromatin Immunoprecipitation
  • ELISA
  • Immunoprecipitation
  • Western Blot 1:500
• Application Notes: The quality control of this antibody is limited to Western blot on the immunizing protein. It has also been used for ELISA. Abnova's recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500 Use in chromatin Immunoprecipitation and Immunoprecipitation reported in scientific literature (PMID 21170338)

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Unpurified antisera so the specific antibody concentration is unknown. Contains 50% glycerol.
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ZNF274 Antibody

• GIOT2
• GIOT-2
• gonadotropin inducible transcription repressor-2
• Gonadotropin-inducible ovary transcription repressor 2
• gonadotropin-inducible transcription repressor 2
• KOX7DKFZp434F1811
• zinc finger protein 44 (KOX 7)
• zinc finger protein 44
• Zinc finger protein 55DKFZp686L21136
• Zinc finger protein 58ZNF504
• Zinc finger protein KOX7
• zinc finger protein ZnFP12
• ZNF
• ZNF55
• ZNF58

Background

This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ZNF274 Antibody (H00010782-A01)(1)

Publication using H00010782-A01

• Frietze S, O'Geen H, Blahnik KR et al. ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes. PLoS One 2010-12-08 [PMID: 21170338]

Bioinformatics

• Gene Symbol: ZNF274
• Entrez:
  • 10782(Human)
• OMIM:
  • 605467(Human)
• Uniprot:
  • NP_598009(Human)