WIPI1 Antibody (3C1)

Images

 
Western Blot: WIPI1 Antibody (3C1) [H00055062-M02] - WIPI1 monoclonal antibody (M02), clone 3C1 Analysis of WIPI1 expression in PC-12.
Sandwich ELISA: WIPI1 Antibody (3C1) [H00055062-M02] - Detection limit for recombinant GST tagged WIPI1 is 0.03 ng/ml as a capture antibody.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, ELISA
Clone
3C1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

WIPI1 Antibody (3C1) Summary

Immunogen
WIPI1 (NP_060453, 348 a.a. ~ 446 a.a) partial recombinant protein with GST tag.GGECVLIKTHSLLGSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIILCRGNQKGKTKQ
Specificity
WIPI1 (3C1)
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
WIPI1
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Reactivity Notes

Human, Rat.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for WIPI1 Antibody (3C1)

  • Atg18 protein homolog
  • Atg18
  • ATG18A
  • FLJ10055
  • WD repeat domain phosphoinositide-interacting protein 1
  • WD repeat domain, phosphoinositide interacting 1
  • WD40 repeat protein interacting with phosphoinositides of 49 kDa
  • WD40 repeat protein Interacting with phosphoInositides of 49kDa
  • WIPI 49 kDa
  • WIPI-1 alpha
  • WIPI-1
  • WIPI49ATG18

Background

WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI1, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for WIPI1 Antibody (H00055062-M02)

Discover related pathways, diseases and genes to WIPI1 Antibody (H00055062-M02). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on WIPI1.

WIPI1 - An essential regulator of early autophagosome assembly
WD repeat domain phosphoinositide-interacting protein 1 (WIPI) is involved in the lysosomal degradation of cytoplasmic components during starvation-induced autophagy. WIPI1 is a seven bladed beta-propeller protein that provides a scaffold for the ...  Read full blog post.

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Bioinformatics

Gene Symbol WIPI1
Entrez
OMIM
Uniprot