VIPR1/VPAC1 Antibody - BSA Free

Immunohistochemistry-Paraffin: VIPR1/VPAC1 Antibody [NLS1297] - Analysis of anti-VIP Receptor 1 antibody with human adipocytes.

• Reactivity: Hu, Pm, Pm
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

VIPR1/VPAC1 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human VIPR1/VPAC1.
• Epitope: 3rd cytoplasmic domain
• Localization: Plasma membrane
• Specificity: Human VIPR1/VPAC1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Primate (100%), Monkey (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: VIPR1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml
• Application Notes: .

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (88%), Rabbit (88%), Mouse (81%), Rat (81%), Bovine (81%), Guinea pig (81%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for VIPR1/VPAC1 Antibody - BSA Free

• FLJ41949
• HVR1
• II
• PACAP type II receptor
• PACAP-R2
• RDC1
• type II
• V1RG
• vasoactive intestinal peptide receptor 1
• vasoactive intestinal polypeptide receptor 1
• VIP R1
• VIP receptor, type I
• VIPR
• VIPR1
• VPAC1
• VPAC1R

Background

Vasoactive Intestinal Polypeptide Receptor 1 (VIPR1) is a member of the Vasoactive Intestinal Polypeptide subfamily. Vasoactive intestinal peptide (VIP) plays multiple roles in the nervous, endocrine, and immune systems as a neurotransmitter, a hormone, and a cytokine. VIPR1, a receptor for VIP, has been shown to expressed widely in normal tissues and is the predominant receptor subtype for VIP in cancers. VIP and its receptors, VIPR1 and VIPR2, are highly expressed in the immune system and modulate diverse T cell functions. Recently VIP-R1 has been shown to be a novel and potent facilitator of HIV-1 infection. Two isoforms are produced by alternative splicing. VIPR1 expression has been documented widely in normal and cancerous tissues, including adipose, adrenal, bladder, blood, brain, breast, colon, ganglion, GI tract, heart, kidney, liver, lung, lymph node, ovary, pancreas, placenta, prostate, skin, small intestine, spinal cord, spleen, stomach, testis, thymus, thyroid, and vessel. ESTs have been isolated from a diverse set of normal and cancerous tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VIPR1
• Entrez:
  • 7433(Human)
• Uniprot:
  • P32241(Human)