Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Immunogen affinity purified
Reconstitute at 0.2 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for KLF6 Antibody
B-cell-derived protein 1
core promoter element binding protein
Core promoter element-binding protein
GC-rich binding factor
GC-rich sites-binding factor GBF
Krueppel-like factor 6
Kruppel-like factor 6
Kruppel-like zinc finger protein Zf9
protooncogene B-cell derived 1
suppression of tumorigenicity 12 (prostate)
Suppressor of tumorigenicity 12 protein
Transcription factor Zf9
KLF6 is a ubiquitously expressed nuclear protein belonging to the Kruppel C2H2-type zinc finger transcription factor family. It is a 283 amino acid (aa) protein that contains an N-terminal acidic domain, a Ser/Thr-rich region and three zinc-finger motifs. The acidic region may interact with other transcription factors. The Ser-Thr-rich region likely serves as an activation domain, and the zinc-finger motifs bind DNA. One alternate splice form is known that shows a 55 aa substitution for the C-terminal 57 amino acids. KLF6 is considered a tumor-suppressor gene. It also promotes iNOS and TGF-beta 1 expression. Human KLF6 shares 94%, 95% and 94% aa sequence identity with rat, mouse and canine KLF6, respectively.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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