VIPR1/VPAC1 Products

Description

The Vasoactive Intestinal Polypeptide Receptor 1 (VPAC1) is a member of a family of three G-protein coupled receptors which mediate VIP (vasoactive intestinal peptide; a small neuropeptide) and PACAP (pituitary adenlyate cyclase activating peptide) function in a variety of tissues. Together, the VPAC1 and VPAC2 receptors compose a subtype of the VIP receptor. Expression of the VIP and PACAP receptors has been linked to the presence of human tumors. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase.

Bioinformatics

Entrez	22354 Mouse 24875 Rat 7433 Human
Uniprot	AAH64424 Human AAH64424.1 Human NP_004615 Human P32241 Human
Product By Gene ID	7433
Alternate Names	FLJ41949 HVR1 II PACAP type II receptor type II vasoactive intestinal peptide receptor 1 vasoactive intestinal polypeptide receptor 1 VIP receptor, type I

Diseases related to VIPR1/VPAC1

Discover more about diseases related to VIPR1/VPAC1.

Pituitary Diseases
Neoplasms
Nervousness
Inflammation
Malignant Neoplasms
Disease Of Adrenal Medulla
Lymphoma
Observation Of Neuromuscular Block
Malignant Neoplasm Of Prostate
Carcinoma
Adenocarcinoma
Prostatic Neoplasms
Malignant Neoplasm Of Lung
Lung Neoplasms
Leukemia
Acute-phase Reaction
Pheochromocytoma
Rheumatoid Arthritis
Schistosomiasis

Pathways for VIPR1/VPAC1

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Secretion
Localization
Pathogenesis
Cell Proliferation
Chemotaxis
Reverse Transcription
Cytokine Production
Cell Migration
Immune Response
Inflammatory Response
Translation
Acute-phase Response
Cell Differentiation
Cell Chemotaxis
T Cell Migration
Insulin Secretion
Cell Adhesion
Transport
Cell Activation
Chemokine Production

Research Areas for VIPR1/VPAC1

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Cancer
Cell Cycle and Replication
GPCR
Neuroscience
Neurotransmission
Signal Transduction

PTMs for VIPR1/VPAC1

Learn more about PTMs related to VIPR1/VPAC1.

Phosphorylation
Cleavage

Bioinformatics Tool for VIPR1/VPAC1

Discover related pathways, diseases and genes to VIPR1/VPAC1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.