VIP Antibody

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

VIP Antibody Summary

Immunogen
Synthetic peptide corresponding to part of the native molecule conjugated to Keyhole limpet Haemocyanin.
Localization
Secreted
Specificity
NB100-65658 is specific for vasoactive intestinal peptide.In IHC-paraffin positive staining is seen in the ganglion cells in both the superficial and deep plexus of the wall on the human small bowel.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
VIP
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Human. Based on sequence similarity, is expected to react with: Bovine, Dog, Horse, Mouse, Pig, Rhesus Monkey, Rat, Sheep.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for VIP Antibody

  • MGC13587
  • PHM27
  • vasoactive intestinal peptide
  • VIP peptides
  • VIP

Background

Vasoactive Intestinal Peptide (VIP), a 28 amino acid peptide originally isolated from porcine duodenum, is present not only in gastrointestinal tissues but also in neural tissues, possibly as a neurotransmitter, and exhibits a wide variety of biological actions. It belongs to the glucagon family, and in the duodenum is known to stimulate myocardial contractility, cause vasodilation, increase glycogenolysis, lower arterial blood pressure and relax the smooth muscle of trachea, stomach and gall bladder. Ectopic endocrine tumors secreting VIP (VIPomas) give rise to raised plasma levels of VIP and are associated with watery diarrhea, hypokalemia and achlorhydria syndrome. This antibody detects ganglion cells in both the superficial and deep plexus of the wall of the small bowel in human. The VIP producing tumors are usually neuroblastomas of endocrine tumors in the pancreas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics Tool for VIP Antibody (NB100-65658)

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Diseases for VIP Antibody (NB100-65658)

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Bioinformatics

Gene Symbol VIP
Entrez
Uniprot