Vanilloid R1/TRPV1 Antibody Summary
Immunogen |
Synthetic peptide: RASLDSEESESPPQENSC, corresponding to amino-terminus of Rat VR1, amino acids 4-21. |
Localization |
Plasma membrane |
Specificity |
Vanilloid Receptor 1 |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
TRPV1 |
Purity |
Unpurified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/Immunofluorescence 1:1000
- Immunohistochemistry 1:10-1:500
- Immunohistochemistry-Frozen
- Immunohistochemistry-Paraffin 1:1000
- Immunoprecipitation 1:10-1:500
- Western Blot 1:100-1:2000
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Application Notes |
Optimal dilution should be determined by investigator. IHC-Frozen reactivity reported in scientific literature (PMID: 23573230), Immunoprecipitation reactivity reported in scientific literature (PMID: 25801060). |
Control Peptide |
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Publications |
Read Publications using NB100-1617 in the following applications:
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Reactivity Notes
Mouse reactivity reported in scientific literature (PMID: 25801060).
Packaging, Storage & Formulations
Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
Buffer |
Whole antisera |
Preservative |
0.05% Sodium Azide |
Purity |
Unpurified |
Alternate Names for Vanilloid R1/TRPV1 Antibody
Background
Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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Video Protocols
FAQs for Vanilloid R1/TRPV1 Antibody (NB100-1617) (0)
Secondary Antibodies
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Isotype Controls
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