Recombinant Human VAMP-8 Protein

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SDS-Page: VAMP8 Protein [NBC1-18348] - VAMP8, 10.9kDa (96aa), confirmed by MALDI-TOF with a purity of 95% by SDS PAGE

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.25 mg/ml

Order Details

Recombinant Human VAMP-8 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-76 of Human VAMP-8

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MEEASEGGGN DRVRNLQSEV EGVKNIMTQN VERILARGEN LEHLRNKTED LEATSEHFKT TSQKVARKFW WKNVKM

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
VAMP8
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
10.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris pH8.5. 0.1mM PMSF, 0.2M NaCl, 50% glycerol, 0.1M Imidazole
Preservative
No Preservative
Concentration
0.25 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human VAMP-8 Protein

  • EDB
  • EDBVAMP-8
  • Endobrevin
  • VAMP8
  • VAMP-8
  • vesicle-associated membrane protein 8 (endobrevin)
  • vesicle-associated membrane protein 8

Background

Vehicle-associated membrane (VAMP8),also known as endobrevin, is the main components of a SNARE complex involved in the docking and fusion of synaptic vesicles with the presynaptic membrane. This protein plays a role in regulated enzyme secretion in pancreatic acinar cells and is involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. It is required for dense-granule secretion in platelets. Recombinant VAMP8 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol VAMP8
Entrez