UNC5H2/UNC5B Antibody

Western Blot: UNC5H2/UNC5B Antibody [NBP2-42523] - Analysis of Human Bone Marrow lysate (35 ug protein in RIPA buffer) with (B) and without (A) blocking with the immunizing peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

• Reactivity: Hu, Mu, Rt, Po, Bv, Ca
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

UNC5H2/UNC5B Antibody Summary

• Immunogen: Peptide with sequence C-SARDWIFQLKTQAHQ corresponding to internal region according to NP_734465.2.
• Predicted Species: Mouse (100%), Rat (100%), Porcine (100%), Bovine (100%), Canine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: UNC5B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:64000
  • Western Blot 1 - 3 ug/ml
• Application Notes: WB: Approx. 90 kDa band observed in human bone marrow lysates (calculated MW of 104 kDa band according to NP_734465.2). Some minor background is detected and is blocked by the immunizing peptide. We call for caution when used for other assays than WB.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for UNC5H2/UNC5B Antibody

• p53RDL1
• p53-regulated receptor for death and life protein 1
• Protein unc-5 homolog 2
• Protein unc-5 homolog B
• transmembrane receptor Unc5H2
• unc5 (C.elegans homolog) b
• unc-5 homolog 2
• unc-5 homolog B (C. elegans)
• UNC5B
• UNC5H2
• UNC5H2netrin receptor UNC5B

Background

UNC5B - unc-5 homolog B (C. elegans)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for UNC5H2/UNC5B Antibody (NBP2-42523)(1)

Publication using NBP2-42523

• Tang X, Jang SW, Okada M et al. Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B. Nat Cell Biol 2008-06-01 [PMID: 18469807]

Bioinformatics

• Gene Symbol: UNC5B
• Entrez:
  • 219699(Human)
  • 107449(Mouse)
  • 60630(Rat)