UNC5H2/UNC5B Antibody

• Reactivity: Hu, Mu, Rt, Bv, Ca
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

UNC5H2/UNC5B Antibody Summary

• Description: Please note, this antibody is considered to be "Innovators Grade". Innovators Grade antibodies have been validated for limited uses and require additional characterization for most new species/applications. These antibodies are directed against antigens that have limited or no commercial antibodies available for them, or for which there are limited expression data available to us. In an effort to encourage customer feedback, Novus has made these antibodies available through our Innovators Reward program. Under this program, Novus will provide you a 50% refund on the purchased product as well as a 50% discount on a future product of equal value in exchange for your new data. Please contact us at innovators@novusbio.com for more details.
• Immunogen: Peptide with sequence C-DWIFQLKTQAHQGH corresponding to internal region according to NP_084046.2.
• Specificity: This antibody is expected to recognize the cytoplasmic domain of the protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: Unc5b
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:16000
  • Western Blot 1:100 - 1:2000
• Application Notes: WB: Preliminary experiments in human and rodent brain, lung and spleen lysates gave no specific signal but low background.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for UNC5H2/UNC5B Antibody

• p53RDL1
• p53-regulated receptor for death and life protein 1
• Protein unc-5 homolog 2
• Protein unc-5 homolog B
• transmembrane receptor Unc5H2
• unc5 (C.elegans homolog) b
• unc-5 homolog 2
• unc-5 homolog B (C. elegans)
• UNC5B
• UNC5H2
• UNC5H2netrin receptor UNC5B

Background

UNC5B - unc-5 homolog B (C. elegans)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for UNC5H2/UNC5B Antibody (NBP2-26090)(1)

Publication using NBP2-26090

• Koch AW, Mathivet T, Larrivee B et al. Robo4 maintains vessel integrity and inhibits angiogenesis by interacting with UNC5B. Dev Cell 2011-01-18 [PMID: 21238923]

Bioinformatics

• Gene Symbol: Unc5b
• Entrez:
  • 219699(Human)
  • 107449(Mouse)
  • 60630(Rat)