ULBP-4/RAET1E Antibody (709116) [Allophycocyanin/Cy7]

• Reactivity: Hu
• Applications: Flow
• Clone: 709116
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin/Cy7

ULBP-4/RAET1E Antibody (709116) [Allophycocyanin/Cy7] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human ULBP‑4/RAET1E
  Gly30-Asp225
  Accession # Q8TD07
• Specificity: Detects human ULBP-4/RAET1E in direct ELISAs and Western blots. In Western blots, approximately 20% cross-reactivity with recombinant human (rh) ULBP-2 is observed and no cross-reactivity with rhULBP-1 or rhULBP-3 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: RAET1E
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for ULBP-4/RAET1E Antibody (709116) [Allophycocyanin/Cy7]

• bA350J20.7
• LETAL
• LETALRAE-1-like transcript 4
• Lymphocyte effector toxicity activation ligand
• MGC125309
• N2DL4
• N2DL-4
• NKG2D ligand 4
• NKG2DL4
• RAET1E
• RAET1E2
• retinoic acid early transcript 1ERL-4
• RL-4
• ULBP4
• ULBP-4
• ULBP4MGC125308

Background

Members of the RAET1 family, such as RAET1E, are major histocompatibility complex (MHC) class I-related genes located within a 180-kb cluster on chromosome 6q24.2-q25.3. RAET1 proteins contain MHC class I-like alpha-1 and alpha-2 domains. RAET1E and RAET1G (MIM 609244) differ from the other RAET1 proteins (e.g., RAET1I, or ULBP1; MIM 605697) in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. (Radosavljevic et al., 2002 [PubMed 11827464]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RAET1E